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公开(公告)号：US20160228436A1
公开(公告)日：2016-08-11
申请号：US15029617
申请日：2014-10-17
Inventor： Mary E. Reyland , Sten Wie , James DeGregori
IPC: A61K31/506 , A61K31/5025 , A61K31/496 , A61K31/517
CPC classification number: A61K31/506 , A61K31/496 , A61K31/5025 , A61K31/517 , A61K45/06 , A61K2300/00
Abstract: The present invention provides methods for reducing apoptosis of non-cancerous cells during a cancer treatment and beneficial effects associated with reducing such apoptosis. In particular, methods of the invention comprise administering a tyrosine kinase inhibitor to a cancer patient who is undergoing cancer treatment in order to reduce apoptosis of non-cancerous cells.
Abstract translation: 本发明提供了在癌症治疗期间减少非癌细胞凋亡的方法以及与减少这种凋亡有关的有益效果。 特别地，本发明的方法包括向正在进行癌症治疗的癌症患者施用酪氨酸激酶抑制剂，以减少非癌细胞的凋亡。
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公开(公告)号：US11376247B2
公开(公告)日：2022-07-05
申请号：US16619289
申请日：2018-06-05
Inventor： Mary Reyland , Sten Wie
IPC: A61K31/496 , A61P43/00 , A61K31/4025 , A61K31/5025 , A61K31/506
Abstract: Methods for inducing the regeneration of non-cancerous tissues in a cancer patient undergoing radiotherapy and/or chemotherapy using continuous administration of tyrosine kinase inhibitors for at least 90 days following a cancer treatment in the patient.
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公开(公告)号：US10076520B2
公开(公告)日：2018-09-18
申请号：US15029617
申请日：2014-10-17
Inventor： Mary E. Reyland , Sten Wie , James DeGregori
IPC: A61K31/506 , A61K31/5025 , A61K31/517 , A61K45/06 , A61K31/496
CPC classification number: A61K31/506 , A61K31/496 , A61K31/5025 , A61K31/517 , A61K45/06 , A61K2300/00
Abstract: The present invention provides methods for reducing apoptosis of non-cancerous cells during a cancer treatment and beneficial effects associated with reducing such apoptosis. In particular, methods of the invention comprise administering a tyrosine kinase inhibitor to a cancer patient who is undergoing cancer treatment in order to reduce apoptosis of non-cancerous cells.
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