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公开(公告)号:US20200278355A1
公开(公告)日:2020-09-03
申请号:US16650810
申请日:2018-09-27
Applicant: THE SCRIPPS RESEARCH INSTITUTE
Inventor: Benjamin F. CRAVATT , Liron BAR-PELED , Esther KEMPER
IPC: G01N33/68 , C07C233/05
Abstract: Disclosed herein, in certain embodiments, are protein-probe adducts and synthetic ligands that inhibit protein-probe adduct formation, in which the proteins are regulated by NRF2. In some instances, also described herein are protein-binding domains that interact with a probe and/or a ligand described herein, in which the proteins are regulated by NRF2.