公开(公告)号：US20230241195A1

公开(公告)日：2023-08-03

申请号：US18009095

申请日：2021-06-10

Applicant: THE TEXAS A&M UNIVERSITY SYSTEM

Inventor： Jamie B. Felix ,  Sankar P. Chaki ,  Walter E. Cook ,  Allison Ficht ,  Thomas A. Ficht

IPC: A61K39/07 ,  A61K9/00 ,  A61K9/50 ,  A61K9/48

CPC classification number: A61K39/07 ,  A61K9/0053 ,  A61K9/5052 ,  A61K9/4866 ,  A61K2039/52

Abstract: Methods and compositions for the immunization of animals and humans using an oral immunization or vaccine that comprises B. anthracis Sterne strain 34F2 spores suspended in alginate and coated with a shell containing poly-L-lysine (PEL), a vitelline protein B (VpB), or both and an external coating of alginate in an amount sufficient to protect an animal or human from a lethal dose of anthrax.