专利检索 ap:("THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK") AND inv:"Katherine XU" 第 1 页

1.

发明申请
METHODS OF TREATING VOLUME DEPLETION AND KIDNEY INJURY 审中-公开

公开(公告)号：US20190064166A1

公开(公告)日：2019-02-28

申请号：US15752230

申请日：2016-08-12

申请人： THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

发明人： Jonathan BARASCH , Katherine XU , Paul ROSENSTIEL , Paolo GUARNIERI

IPC分类号： G01N33/573 , G01N33/68 , G01N33/70

摘要： The present invention provides methods for treatment of volume-dependent Acute Kidney Injury (vAKI) and ischemic Acute Kidney Injury (iAKI), as well as methods for diagnosing vAKI and iAKI. The methods are based on determining the levels of PAPPA2, NGAL, KRT20, or TAC-STD2 protein in a sample from a patient, such as a urine sample. The present invention also provides a device and a diagnostics kit for determining whether a sample from a subject contains PAPPA2, NGAL, KRT20, or TACSTD2 protein.