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公开(公告)号:US20240390882A1
公开(公告)日:2024-11-28
申请号:US18719574
申请日:2022-12-16
Applicant: THE TRUSTEES OF PRINCETON UNIVERSITY
Inventor: Paul J. Chirik , Connor S. MacNeil
Abstract: In one aspect, methods for the facile synthesis of cationic cobalt complexes for asymmetric hydrogenation of alkenes are provided. Synthetic methods described herein, in some embodiments, provide Co(I) precatalysts on a time scale and yield permitting catalytic evaluation of a significant number of enantiopure ligands.