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公开(公告)号:US20200277403A1
公开(公告)日:2020-09-03
申请号:US16333196
申请日:2017-09-14
发明人: Andrew TSOURKAS , Burcin ALTUN , Hejia Henry WANG , Feifan YU
摘要: The invention relates to proximity-based sortase-mediated protein purification and ligation. Specifically, the invention relates to techniques that links protein expression/purification with conjugation to therapeutic agents, imaging agents, or linkers.
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公开(公告)号:US20230031853A1
公开(公告)日:2023-02-02
申请号:US17294401
申请日:2019-11-14
发明人: Andrew TSOURKAS , Hejia Henry WANG
IPC分类号: A61K47/68 , A61K9/51 , C07K16/40 , C07K16/18 , A61P35/00 , C07K16/32 , A61K47/64 , A61K47/65
摘要: The invention provides compositions and methods for the cytoplasmic delivery of antibodies and other proteins. Specifically, provided herein are compositions having an anionic polypeptide and a cationic transfection agent for facilitating the cytoplasmic delivery of an antibody or a protein.
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公开(公告)号:US20220235145A1
公开(公告)日:2022-07-28
申请号:US17588205
申请日:2022-01-28
发明人: Andrew TSOURKAS , Burcin ALTUN , Hejia Henry WANG , Feifan YU
摘要: The invention relates to proximity-based sortase-mediated protein purification and ligation. Specifically, the invention relates to techniques that links protein expression/purification with conjugation to therapeutic agents, imaging agents, or linkers.
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