公开(公告)号：US20230263426A1

公开(公告)日：2023-08-24

申请号：US18041229

申请日：2021-08-13

Applicant: THE UAB RESEARCH FOUNDATION

Inventor： Surya P. Bhatt ,  Arie Nakhmani ,  Sandeep Bodduluri

IPC: A61B5/087 ,  A61B5/091 ,  G16H50/20 ,  G16H20/00

CPC classification number: A61B5/087 ,  A61B5/091 ,  G16H50/20 ,  G16H20/00

Abstract: The present disclosure relates to a method of detecting airflow obstruction using one or more novel metrics associated with a spirometry reading for a subject. The method includes obtaining spirometry data from a subject, generating a first measurement curve and a second measurement curve based on the obtained data for the subject, performing at least a first curve-fitting on the first measurement curve using a Least Absolute Residuals algorithm to estimate a function which closely approximates the spirometry data for the subject by minimizing a sum of absolute deviation, determining a first metric that describes a rate of volume increase based on the estimated function, comparing the first metric to one or more threshold values, and determining a presence or absence of airflow obstruction for the subject based on the comparison of the first metric to the one or more threshold values.