公开(公告)号：US20250073221A1

公开(公告)日：2025-03-06

申请号：US18949880

申请日：2024-11-15

Applicant: THE UNIVERSITY OF ADELAIDE

Inventor： Rebecca Louise Robker ,  Macarena Bermudez Gonzalez

IPC: A61K31/4545 ,  A01N1/02 ,  C12N5/076

Abstract: Disclosed are methods and products for improving the quality of sperm, methods for treating subjects to improve sperm quality or improve fertility, and use of sperm with improved quality in assisted reproductive technologies, including exposing the sperm to BGP-15 and/or a derivative thereof, such as BGP-15, propanolol, bimoclomol, arimoclomal, NG94, iroxanadine, and/or a pharmaceutically acceptable derivative, prodrug, solvate, salt, tautomer, stereoisomer, and/or racemate thereof.