公开(公告)号：US20210060174A1

公开(公告)日：2021-03-04

申请号：US16644354

申请日：2018-09-07

申请人： THE UNIVERSITY OF BRISTOL

发明人： Adam Willis PERRIMAN ,  Robert Christopher DELLER ,  Wenjin XIAO ,  Thomas Iain Phillip GREEN ,  Benjamin Michael CARTER ,  Graham John DAY ,  Rosalia Cuahtecontzi DELINT

IPC分类号： A61K47/69 ,  A61K47/60 ,  A61L27/18 ,  A61L27/22 ,  C12N9/16

摘要： There is provided a phospholipid composition which is a bilayer or micelle comprising at least one embedded protein-polymer surfactant conjugate comprising an anchor protein, wherein the anchor protein is a cationised protein or an anionised protein, the composition characterised in that the anchor protein is: a) an active enzyme; orb) is a protein which does not comprise a —CH2C(O)NCH3(CH2)3NCH3)2H+ linker covalently bonded to an amino acid side chain.