公开(公告)号：US20150196034A1

公开(公告)日：2015-07-16

申请号：US14347782

申请日：2012-10-01

Applicant: THE UNIVERSITY OF EXETER

Inventor： Mark Wood ,  Matthew Whiteman ,  Alexis Perry

IPC: A01N57/24 ,  C07F9/54 ,  C07F9/6553

CPC classification number: A01N57/24 ,  A61K31/385 ,  A61K31/662 ,  A61K47/54 ,  C07F9/5442 ,  C07F9/655345

Abstract: The invention relates to a compound comprising a mitochondrial targeting group linked to group capable of releasing hydrogen sulfide, or a pharmaceutically acceptable salt thereof, for use in the treatment of the human or animal body by surgery or therapy. The invention also relates to the use of the compound in the treatment of a plant, and to certain forms of the compound.

Abstract translation: 本发明涉及包含与能够释放硫化氢的基团连接的线粒体靶向基团的化合物或其药学上可接受的盐，用于通过手术或治疗来治疗人或动物体。 本发明还涉及该化合物在处理植物和某些形式的化合物中的用途。

公开(公告)号：US10058100B2

公开(公告)日：2018-08-28

申请号：US14347782

申请日：2012-10-01

Applicant: THE UNIVERSITY OF EXETER

Inventor： Mark Wood ,  Matthew Whiteman ,  Alexis Perry

IPC: A01N57/24 ,  C07F9/54 ,  C07F9/6553 ,  A61K31/662 ,  A61K47/48 ,  A61K31/385

CPC classification number: A01N57/24 ,  A61K31/385 ,  A61K31/662 ,  A61K47/54 ,  C07F9/5442 ,  C07F9/655345

Abstract: The invention relates to a compound comprising a mitochondrial targeting group linked to group capable of releasing hydrogen sulfide, or a pharmaceutically acceptable salt thereof, for use in the treatment of the human or animal body by surgery or therapy. The invention also relates to the use of the compound in the treatment of a plant, and to certain forms of the compound.