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公开(公告)号:US4937263A
公开(公告)日:1990-06-26
申请号:US380834
申请日:1989-07-17
IPC分类号: C07D309/30
CPC分类号: C07D309/30
摘要: Novel 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors which are useful as antihypercholesterolemic agents and are represented by the following general structural formulae (I) and (II): ##STR1## and pharmaceutically acceptable salts of the compounds (II) in which Z is hydrogen are disclosed.
摘要翻译: 新颖的3-羟基-3-甲基戊二酰辅酶A(HMG-CoA)还原酶抑制剂,其可用作抗高胆固醇血症药,并由以下通式(I)和(II)表示:(II) )和其中Z为氢的化合物(II)的药学上可接受的盐。
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公开(公告)号:US4876279A
公开(公告)日:1989-10-24
申请号:US199829
申请日:1988-05-26
IPC分类号: C07D309/30
CPC分类号: C07D309/30
摘要: Novel 3-hydroxy-3-methylglutaryl-Coenzyme A(HMG-CoA) reductase inhibitors, which are useful as antihypercholesterolemic agents and are represented by the following general structural formulae (I) and (II) ##STR1## and pharmaceutically acceptable salts of the compound (II) in which Z is hydrogen are disclosed.
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公开(公告)号:US4771071A
公开(公告)日:1988-09-13
申请号:US859535
申请日:1986-05-05
IPC分类号: C07D309/30 , A61K31/365
CPC分类号: C07D309/30 , Y10S514/824
摘要: Novel 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors which are useful as antihypercholesterolemic agents and are represented by the following general structural formulae (I) and (II): ##STR1## and pharmaceutically acceptable salts of the compounds (II) in which Z is hydrogen are disclosed.
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公开(公告)号:US5049696A
公开(公告)日:1991-09-17
申请号:US366085
申请日:1989-06-14
IPC分类号: C07D309/30
CPC分类号: C07D309/30
摘要: Novel 3-hydroxy-3-methylglutaryl-Coenzyme A(HMG-CoA) reductase inhibitors, which are useful as antihypercholesterolemic agents and are represented by the following general structural formulae (I) and (II) ##STR1## and pharmaceutically acceptable salts of the compound (II) in which Z is hydrogen are disclosed.
摘要翻译: 新型3-羟基-3-甲基戊二酰辅酶A(HMG-CoA)还原酶抑制剂,其可用作抗高胆固醇血症药物并由以下通式(I)和(II)表示。 (II)和其中Z为氢的化合物(II)的药学上可接受的盐。
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公开(公告)号:US4876366A
公开(公告)日:1989-10-24
申请号:US205407
申请日:1988-06-10
IPC分类号: C07D309/30
CPC分类号: C07D309/30
摘要: Novel 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors which are useful as antihypercholesterolemic agents and are represented by the following general structural formulae (I) and (II): ##STR1## and pharmaceutically acceptable salts of the compounds (II) in which Z is hydrogen are disclosed.
摘要翻译: 新颖的3-羟基-3-甲基戊二酰辅酶A(HMG-CoA)还原酶抑制剂,其可用作抗高胆固醇血症药,并由以下通式(I)和(II)表示:(II) )和其中Z为氢的化合物(II)的药学上可接受的盐。
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公开(公告)号:US4864038A
公开(公告)日:1989-09-05
申请号:US205406
申请日:1988-06-10
IPC分类号: C07D309/30
CPC分类号: C07D309/30
摘要: Novel 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors which are useful as antihypercholesterolemic agents and are represented by the following general structural formulae (I) and (II): ##STR1## and pharmaceutically acceptable salts of the compounds (II) in which Z is hydrogen are disclosed.
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公开(公告)号:US4937264A
公开(公告)日:1990-06-26
申请号:US377665
申请日:1989-06-30
IPC分类号: C07D309/30
CPC分类号: C07D309/30
摘要: Novel 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors which are useful as antihypercholesterolemic agents and are represented by the following general structural formulae (I) and (II): ##STR1## and pharmaceutically acceptable salts of the compounds (II) in which Z is hydrogen are disclosed.
摘要翻译: 新颖的3-羟基-3-甲基戊二酰辅酶A(HMG-CoA)还原酶抑制剂,其可用作抗高胆固醇血症药物并由以下通式(I)和(II)表示:
(II)和其中Z为氢的化合物(II)的药学上可接受的盐。 -
公开(公告)号:US4847306A
公开(公告)日:1989-07-11
申请号:US177806
申请日:1988-04-11
IPC分类号: C07D309/30
CPC分类号: C07D309/30
摘要: Novel 3-hydroxy-3-methylglutaryl-Coenzyme A(HMG-CoA) reductase inhibitors, which are useful as antihypercholesterolemic agents and are represented by the following general structural formulae (I) and (II) ##STR1## and pharmaceutically acceptable salts of the compound (II) in which Z is hydrogen are disclosed.
摘要翻译: 新型3-羟基-3-甲基戊二酰辅酶A(HMG-CoA)还原酶抑制剂,其可用作抗高胆固醇血症药物并由以下通式(I)和(II)表示。 (II)和其中Z为氢的化合物(II)的药学上可接受的盐。
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公开(公告)号:US4766145A
公开(公告)日:1988-08-23
申请号:US859525
申请日:1986-05-05
IPC分类号: C07D309/30 , A61K31/785 , A61K31/365
CPC分类号: C07D309/30 , Y10S514/824
摘要: Novel 3-hydroxy-3-methylglutaryl-Coenzyme A(HMG-CoA) reductase inhibitors, which are useful as antihypercholesterolemic agents and are represented by the following general structural formulae (I) and (II) ##STR1## and pharmaceutically acceptable salts of the compound (II) in which Z is hydrogen are disclosed.
摘要翻译: 新型3-羟基-3-甲基戊二酰辅酶A(HMG-CoA)还原酶抑制剂,其可用作抗高胆固醇血症药,并由以下通式(I)和(II)表示: 公开了其中Z为氢的化合物(II)及其药学上可接受的盐。
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10.
公开(公告)号:US4661483A
公开(公告)日:1987-04-28
申请号:US859529
申请日:1986-05-05
IPC分类号: C07D295/185 , C07D309/30 , A61K31/365 , A61K31/535 , C07D413/12
CPC分类号: C07D295/185 , C07D309/30
摘要: Novel 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors which are useful as antihypercholesterolemic agents and are represented by the following general structural formulae (I) and (II): ##STR1## and pharmaceutically acceptable salts of the compounds (II) in which Z is hydrogen are disclosed.
摘要翻译: 新颖的3-羟基-3-甲基戊二酰辅酶A(HMG-CoA)还原酶抑制剂,其可用作抗高胆固醇血症药物并由以下通式(I)和(II)表示:
(II)和其中Z为氢的化合物(II)的药学上可接受的盐。
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