公开(公告)号：US08048866B2

公开(公告)日：2011-11-01

申请号：US11573458

申请日：2004-08-13

申请人： Tadashi Sato ,  Tomokazu Nakai ,  Tsutomu Aritsuka ,  Tetsuo Nanbu ,  Hiroo Sadoya ,  Etsuo Imura

发明人： Tadashi Sato ,  Tomokazu Nakai ,  Tsutomu Aritsuka ,  Tetsuo Nanbu ,  Hiroo Sadoya ,  Etsuo Imura

IPC分类号： A61K31/7016 ,  A61P3/14

CPC分类号： A61K31/7016 ,  A23K20/163 ,  A23K50/10 ,  A23L33/10

摘要： The invention is to develop an agent having at least one of anticalcipenic, antiedemic and diuretic activities for humans or animals and to inhibit the postpartum drop of the calcium concentration in blood, thereby maintaining the health of the mother body and smoothing nursing and lactation.In the invention, difructose anhydride (DFA) being a disaccharide made of two molecules of fructose coupled together is administered. In particular, for inhibiting the postpartum drop of the calcium concentration in blood, DFA III and/or DFA IV is administered before childbirth delivery (in a cow, before an expected date of calving). The joint use of a calcium agent or vitamin D is possible as required.

摘要翻译： 本发明是开发具有至少一种抗人体，抗血尿和利尿活性的人或动物的药剂，并抑制血液中钙浓度的产后下降，从而保持母体的健康，平滑的哺乳和哺乳期。 在本发明中，施用作为由两分子果糖偶联在一起的二糖的双缩水甘油酸酐（DFA）。 特别地，为了抑制血液中钙浓度的产后降低，在分娩前（在产犊之前的牛中，）施用DFA III和/或DFA IV。 根据需要可以联合使用钙剂或维生素D。

公开(公告)号：US20090209484A1

公开(公告)日：2009-08-20

申请号：US11573458

申请日：2004-08-13

申请人： Tadashi Sato ,  Tomokazu Nakai ,  Tsutomu Aritsuka ,  Tetsuo Nanbu ,  Hiroo Sadoya ,  Etsuo Imura

发明人： Tadashi Sato ,  Tomokazu Nakai ,  Tsutomu Aritsuka ,  Tetsuo Nanbu ,  Hiroo Sadoya ,  Etsuo Imura

IPC分类号： A61K31/7016 ,  C13K11/00 ,  A61P13/00

CPC分类号： A61K31/7016 ,  A23K20/163 ,  A23K50/10 ,  A23L33/10

摘要： The invention is to develop an agent having at least one of anricalclpenic, antiedemic and diuretic activities for humans or animals and to inhibit the postpartum drop of the calcium concentration in blood, thereby maintaining the health of the mother body and smoothing nursing and lactation.In the invention, difructose anhydride (DTA) being a disaccharide made of two molecules of fructose coupled together is administered. In particular, for inhibiting the postpartum drop of the calcium concentration in blood, DFA III and/or DFA IV is administered before childbirth delivery (in a cow, before an expected date of calving). The joint use of a calcium agent or vitamin D is possible as required.

摘要翻译： 本发明是开发一种具有至少一种人或动物的止痛，抗焦虑和利尿活性的药剂，并抑制血液中钙浓度的产后降低，从而保持母体的健康和平滑的哺乳和哺乳期。 在本发明中，施用由两个分别连接在一起的果糖制成的二糖的双缩水甘油酸酐（DTA）。 特别地，为了抑制血液中钙浓度的产后降低，在分娩前（在产犊之前的牛中，）施用DFA III和/或DFA IV。 根据需要可以联合使用钙剂或维生素D。