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公开(公告)号：US5059612A
公开(公告)日：1991-10-22
申请号：US578655
申请日：1990-09-07
申请人： Taiichiro Imanishi , Yasuyuki Ichimaru , Aiko Sawa , Fukio Konno , Helmut Wachtel , Showa Ueki , Michihiro Fujiwara , Tsuneyuki Yamamoto
发明人： Taiichiro Imanishi , Yasuyuki Ichimaru , Aiko Sawa , Fukio Konno , Helmut Wachtel , Showa Ueki , Michihiro Fujiwara , Tsuneyuki Yamamoto
IPC分类号： C07D207/24 , A61K31/40 , A61P25/28
CPC分类号： A61K31/40
摘要： The invention relates to a method of treating dementia, such as cerebro-vascular dementia, for example, multiple infarct dementia and amyloid angiopathic dementia, cerebro-parenchymatous dementia, such as Alzheimer's dementia and Pick's disease, and dementia caused by brain tumor, hydrocephalus, hepatic meningitis, cerebral trauma, or cerebral function disorders, comprising administering rolipram.
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公开(公告)号：US08318799B2
公开(公告)日：2012-11-27
申请号：US12851091
申请日：2010-08-05
IPC分类号： A61K31/343 , A61P25/30
CPC分类号： A61K31/343
摘要： The present invention provides a therapeutic agent for substance dependence, which prevents relapse/recurrence of compulsive substance-taking behavior based on craving for addictive substances such as stimulant substances, opioids, barbiturate type anesthetics, hallucinogens, cocaine, hemp, cannabis, alcohol, or volatile organic solvents. (−)-1-(Benzofuran-2-yl)-2-propylaminopentane or a pharmacologically acceptable acid addition salt thereof is useful as a therapeutic agent for substance dependence, which prevents relapse/recurrence of compulsive substance-taking behavior associated with craving for addictive substances.
摘要翻译： 本发明提供了用于物质依赖的治疗剂，其基于对兴奋剂物质，阿片样物质，巴比妥类型麻醉剂，致幻剂，可卡因，大麻，大麻，酒精等成瘾物质的渴望，防止强迫性物质摄取行为的复发/复发 挥发性有机溶剂。 （ - ） - 1-（苯并呋喃-2-基）-2-丙氨基戊烷或其药理学上可接受的酸加成盐可用作物质依赖性的治疗剂，其可防止与渴望相关的强制性物质摄取行为的复发/复发 成瘾物质
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公开(公告)号：US20080004337A1
公开(公告)日：2008-01-03
申请号：US11791116
申请日：2005-11-21
IPC分类号： A61K31/343 , A61P25/30 , A61P25/32 , A61P25/36
CPC分类号： A61K31/343
摘要： The present invention provides a therapeutic agent for substance dependence, which prevents relapse/recurrence of compulsive substance-taking behavior based on craving for addictive substances such as stimulant substances, opioids, barbiturate type anesthetics, hallucinogens, cocaine, hemp, cannabis, alcohol, or volatile organic solvents. (−)-1-(Benzofuran-2-yl)-2-propylaminopentane or a pharmacologically acceptable acid addition salt thereof is useful as a therapeutic agent for substance dependence, which prevents relapse/recurrence of compulsive substance-taking behavior associated with craving for addictive substances.
摘要翻译： 本发明提供了用于物质依赖的治疗剂，其基于对兴奋剂物质，阿片样物质，巴比妥类型麻醉剂，致幻剂，可卡因，大麻，大麻，酒精等成瘾物质的渴望，防止强迫性物质摄取行为的复发/复发 挥发性有机溶剂。 （ - ） - 1-（苯并呋喃-2-基）-2-丙氨基戊烷或其药理学上可接受的酸加成盐可用作物质依赖性的治疗剂，其可防止与渴望相关的强制性物质摄取行为的复发/复发 成瘾物质
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公开(公告)号：US07825158B2
公开(公告)日：2010-11-02
申请号：US11791116
申请日：2005-11-21
CPC分类号： A61K31/343
摘要： The present invention provides a therapeutic agent for substance dependence, which prevents relapse/recurrence of compulsive substance-taking behavior based on craving for addictive substances such as stimulant substances, opioids, barbiturate type anesthetics, hallucinogens, cocaine, hemp, cannabis, alcohol, or volatile organic solvents. (−)-1-(Benzofuran-2-yl)-2-propylaminopentane or a pharmacologically acceptable acid addition salt thereof is useful as a therapeutic agent for substance dependence, which prevents relapse/recurrence of compulsive substance-taking behavior associated with craving for addictive substances.
摘要翻译： 本发明提供了用于物质依赖的治疗剂，其基于对兴奋剂物质，阿片样物质，巴比妥类型麻醉剂，致幻剂，可卡因，大麻，大麻，酒精等成瘾物质的渴望，防止强迫性物质摄取行为的复发/复发 挥发性有机溶剂。 （ - ） - 1-（苯并呋喃-2-基）-2-丙氨基戊烷或其药理学上可接受的酸加成盐可用作物质依赖性的治疗剂，其可防止与渴望相关的强制性物质摄取行为的复发/复发 成瘾物质
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