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公开(公告)号：US08377476B2
公开(公告)日：2013-02-19
申请号：US12936815
申请日：2009-03-24
CPC分类号： A61K31/137 , A61K8/0208 , A61K8/345 , A61K8/37 , A61K8/41 , A61K8/411 , A61K9/7053 , A61K9/7061 , A61K47/10 , A61K47/14 , A61Q3/00 , A61Q17/005
摘要： Disclosed is a water-based adhesive skin patch which has excellent storage stability, can achieve excellent accumulation of butenafine hydrochloride contained therein on a patched area such as the skin and a nail, and has a high therapeutic effect. Specifically disclosed is a water-based adhesive skin patch containing butenafine hydrochloride, which is characterized by containing butenafine hydrochloride, glycol salicylate and propylene glycol in a water-containing gel ointment. Specifically, butenafine hydrochloride is dissolved in a mixed solution of glycol salicylate and propylene glycol, and the resulting solution is dispersed in a water-containing gel. Particularly, the mixing ratio of glycol salicylate to propylene glycol is 1:2 to 1:30.
摘要翻译： 公开了一种水性粘合性皮肤贴剂，其具有优异的储存稳定性，可以在皮肤和钉子等修补区域上实现含有其中所含的盐酸布他他芬的优异积累，并且具有高治疗效果。 具体公开了含有盐酸布替萘芬的水性粘合性皮肤贴剂，其特征在于在含水凝胶软膏中含有盐酸丁酸，二水杨酸乙酯和丙二醇。 具体地说，将盐酸丁丙
锭溶于水杨酸二乙酯和丙二醇的混合溶液中，将所得溶液分散在含水凝胶中。 特别地，二醇水杨酸酯与丙二醇的混合比为1:2〜1:30。-
公开(公告)号：US20110097407A1
公开(公告)日：2011-04-28
申请号：US12936815
申请日：2009-03-24
CPC分类号： A61K31/137 , A61K8/0208 , A61K8/345 , A61K8/37 , A61K8/41 , A61K8/411 , A61K9/7053 , A61K9/7061 , A61K47/10 , A61K47/14 , A61Q3/00 , A61Q17/005
摘要： Disclosed is a water-based adhesive skin patch which has excellent storage stability, can achieve excellent accumulation of butenafine hydrochloride contained therein on a patched area such as the skin and a nail, and has a high therapeutic effect. Specifically disclosed is a water-based adhesive skin patch containing butenafine hydrochloride, which is characterized by containing butenafine hydrochloride, glycol salicylate and propylene glycol in a water-containing gel ointment. Specifically, butenafine hydrochloride is dissolved in a mixed solution of glycol salicylate and propylene glycol, and the resulting solution is dispersed in a water-containing gel. Particularly, the mixing ratio of glycol salicylate to propylene glycol is 1:2 to 1:30.
摘要翻译： 公开了一种水性粘合性皮肤贴剂，其具有优异的储存稳定性，可以在皮肤和钉子等修补区域上实现含有其中所含的盐酸布他他芬的优异积累，并且具有高治疗效果。 具体公开了含有盐酸布替萘芬的水性粘合性皮肤贴剂，其特征在于在含水凝胶软膏中含有盐酸丁酸，二水杨酸乙酯和丙二醇。 具体地说，将盐酸丁丙
锭溶于水杨酸二乙酯和丙二醇的混合溶液中，将所得溶液分散在含水凝胶中。 特别地，二醇水杨酸酯与丙二醇的混合比为1:2〜1:30。
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