公开(公告)号：US20070231372A1

公开(公告)日：2007-10-04

申请号：US11597321

申请日：2005-05-18

申请人： Takayuki Imamura ,  Noriko Shinya ,  Ryoichi Kawamura ,  Chikateru Nazaki

发明人： Takayuki Imamura ,  Noriko Shinya ,  Ryoichi Kawamura ,  Chikateru Nazaki

IPC分类号： A61L24/00

CPC分类号： A61K38/363 ,  A61K38/4833 ,  A61K45/06 ,  A61L24/0042 ,  A61L24/106

摘要： The present invention relates to a tissue sealant which is safe and effective. In accordance with the present invention, a tissue sealant comprising as an effective ingredient thrombin and fibrinogen characterized in that a bioabsorbable synthetic nonwoven fabric is used as a supporting material; use of a combination of a bioabsorbable synthetic nonwoven fabric as a supporting material and thrombin and fibrinogen as an effective ingredient for a tissue sealant; use of a combination of a bioabsorbable synthetic nonwoven fabric holding thrombin as an effective ingredient, and fibrinogen as an effective ingredient for a tissue sealant; a tissue sealing kit comprising a bioabsorbable synthetic nonwoven fabric holding thrombin as an effective ingredient, and a container comprising fibrinogen as an effective ingredient; and a tissue sealing kit comprising a bioabsorbable synthetic nonwoven fabric as a substrate, a container comprising thrombin as an effective ingredient and a container comprising fibrinogen as an effective ingredient are provided.

摘要翻译： 本发明涉及安全有效的组织密封剂。 根据本发明，包含作为有效成分凝血酶和纤维蛋白原的组织密封剂，其特征在于使用生物可吸收合成无纺布作为支撑材料; 使用生物可吸收合成无纺布作为支撑材料和凝血酶和纤维蛋白原的组合作为组织密封剂的有效成分; 使用保持凝血酶作为有效成分的生物可吸收性合成无纺布和纤维蛋白原作为组织密封剂的有效成分的组合; 包含保持凝血酶作为有效成分的生物可吸收合成无纺布的组织密封试剂盒和包含纤维蛋白原作为有效成分的容器; 提供了包含生物可吸收合成非织造织物作为底物的组织密封套件，包含凝血酶作为有效成分的容器和包含纤维蛋白原作为有效成分的容器。