公开(公告)号：US07718797B2

公开(公告)日：2010-05-18

申请号：US10598303

申请日：2005-03-04

申请人： Takuji Maejima ,  Miki Ohshima

发明人： Takuji Maejima ,  Miki Ohshima

IPC分类号： A61P25/00 ,  A61P9/10 ,  A61K9/08 ,  A61K31/551 ,  C07D403/12

CPC分类号： A61K9/0019 ,  A61K31/551 ,  A61K47/02 ,  C07D401/12

摘要： Fasudil-containing preparations that despite the us of a container excelling in the visibility of contents without particularly blocking of light, exhibit high stability against light; and a method of improving the stability of the preparations against light of storing the same. By regulating the pH value of aqueous solution of fasudil charged in a colorless transparent container to ≦5.5, there can be provided fasudil-containing preparations excelling in stability against light; and can be provided a method of improving the stability of the aqueous solution of fasudil against light, or storing the same.

摘要翻译： 含法舒地尔的制剂，尽管我们的容器具有优异的内容物的可视性，而没有特别阻挡光，表现出高的光稳定性; 以及提高制剂的光稳定性的方法。 通过将装在无色透明容器中的法舒地尔水溶液的pH值调节至5.5，可以提供具有优异光稳定性的含法舒地尔的制剂。 并且可以提供一种改善法舒地尔的水溶液对光的稳定性或存储法舒地尔的方法。

公开(公告)号：US20080234483A1

公开(公告)日：2008-09-25

申请号：US10598303

申请日：2005-03-04

申请人： Takuji Maejima ,  Miki Ohshima

发明人： Takuji Maejima ,  Miki Ohshima

IPC分类号： C07D401/02

CPC分类号： A61K9/0019 ,  A61K31/551 ,  A61K47/02 ,  C07D401/12

摘要： Fasudil-containing preparations that despite the us of a container excelling in the visibility of contents without particularly blocking of light, exhibit high stability against light; and a method of improving the stability of the preparations against light of storing the same. By regulating the pH value of aqueous solution of fasudil charged in a colorless transparent container to ≦5.5, there can be provided fasudil-containing preparations excelling in stability against light; and can be provided a method of improving the stability of the aqueous solution of fasudil against light, or storing the same.

摘要翻译： 含法舒地尔的制剂，尽管我们的容器具有优异的内容物的可视性，而没有特别阻挡光，表现出高的光稳定性; 以及提高制剂的光稳定性的方法。 通过调节装在无色透明容器中的法舒地尔水溶液的pH值为<= 5.5，可以提供具有优异光稳定性的法舒地尔制剂。 并且可以提供一种改善法舒地尔的水溶液对光的稳定性或存储法舒地尔的方法。