专利检索 ap:("Tapan Kanti Das" OR "Tamara Shafer Hodge" OR "Tetsuya Ishino" OR "Nancy Jane Levin" OR "Moorthy Sitharamaiah Suriyanarayana Palanki" OR "Erin Kristen Parsons" OR "Bernard Norman Violand") AND inv:"Nancy Jane Levin" 第 1 页

1.

发明授权
FGF21 conjugates and anti-diabetic uses thereof 失效
标题翻译： FGF21缀合物及其抗糖尿病用途

公开(公告)号：US08722622B2

公开(公告)日：2014-05-13

申请号：US13289533

申请日：2011-11-04

申请人： Tapan Kanti Das , Tamara Shafer Hodge , Tetsuya Ishino , Nancy Jane Levin , Moorthy Sitharamaiah Suriyanarayana Palanki , Erin Kristen Parsons , Bernard Norman Violand

发明人： Tapan Kanti Das , Tamara Shafer Hodge , Tetsuya Ishino , Nancy Jane Levin , Moorthy Sitharamaiah Suriyanarayana Palanki , Erin Kristen Parsons , Bernard Norman Violand

IPC分类号： A61K38/18 , A61K39/395

CPC分类号： C07K16/40 , A61K38/00 , A61K47/6815 , A61K47/6835 , A61K47/6889 , C07K14/50 , C07K2319/30 , C07K2319/31 , C07K2319/75

摘要： The present invention provides a FGF21 molecule covalently attached to the combining site of an antibody via a linker, wherein the linker is covalently attached to the side chain of a linking residue within FGF21. Various uses of the compounds are provided, including methods to prevent or treat diabetes or diabetes-related conditions.

摘要翻译： 本发明提供通过接头共价连接到抗体的结合位点的FGF21分子，其中接头共价连接到FGF21内的连接残基的侧链上。提供了化合物的各种用途，包括预防或治疗糖尿病或糖尿病相关病症的方法。

2.

发明申请
Anti-Diabetic Compounds 失效
标题翻译：抗糖尿病化合物

公开(公告)号：US20120282279A1

公开(公告)日：2012-11-08

申请号：US13289533

申请日：2011-11-04

申请人： Tapan Kanti Das , Tamara Shafer Hodge , Tetsuya Ishino , Nancy Jane Levin , Moorthy Sitharamaiah Suriyanarayana Palanki , Erin Kristan Parsons , Bernard Norman Violand

发明人： Tapan Kanti Das , Tamara Shafer Hodge , Tetsuya Ishino , Nancy Jane Levin , Moorthy Sitharamaiah Suriyanarayana Palanki , Erin Kristan Parsons , Bernard Norman Violand

IPC分类号： A61K39/44 , A61P3/10 , A61P3/04 , A61P3/08 , A61P9/12 , A61P1/16 , A61P9/00 , A61P5/48 , C07K19/00 , A61P3/06

CPC分类号： C07K16/40 , A61K38/00 , A61K47/6815 , A61K47/6835 , A61K47/6889 , C07K14/50 , C07K2319/30 , C07K2319/31 , C07K2319/75

摘要： The present invention provides a FGF21 molecule covalently attached to the combining site of an antibody via a linker, wherein the linker is covalently attached to the side chain of a linking residue within FGF21. Various uses of the compounds are provided, including methods to prevent or treat diabetes or diabetes-related conditions.

摘要翻译： 本发明提供通过接头共价连接到抗体的结合位点的FGF21分子，其中接头共价连接到FGF21内的连接残基的侧链上。提供了化合物的各种用途，包括预防或治疗糖尿病或糖尿病相关病症的方法。