公开(公告)号：US20230045612A1

公开(公告)日：2023-02-09

申请号：US17847811

申请日：2022-06-23

Applicant: Tempest Therapeutics, Inc.

Inventor： Yalda BRAVO ,  Austin Chih-Yu CHEN ,  Jinyue DING ,  Robert GOMEZ ,  Heather LAM ,  Joe Fred NAGAMIZO ,  Renata Marcella OBALLA ,  David Andrew POWELL ,  Tao SHENG

IPC: C07D401/10 ,  C07D209/42 ,  C07D405/12 ,  C07D471/04 ,  C07D403/10 ,  C07D417/10 ,  C07D231/56

Abstract: Compounds, compositions and methods are provided for modulating the activity of EP2 and EP4 receptors, and for the treatment, prevention and amelioration of one or more symptoms of diseases or disorders related to the activity of EP2 and EP4 receptors. In certain embodiments, the compounds are antagonists of both the EP2 and EP4 receptors.

公开(公告)号：US20240150316A1

公开(公告)日：2024-05-09

申请号：US18467022

申请日：2023-09-14

Applicant: Tempest Therapeutics, Inc.

Inventor： Yalda BRAVO ,  Austin Chih-Yu CHEN ,  Jinyue DING ,  Robert GOMEZ ,  Heather LAM ,  Joe Fred NAGAMIZO ,  Renata Marcella OBALLA ,  David Andrew POWELL ,  Tao SHENG

IPC: C07D401/10 ,  C07D209/42 ,  C07D231/56 ,  C07D403/10 ,  C07D405/12 ,  C07D417/10 ,  C07D471/04

CPC classification number: C07D401/10 ,  C07D209/42 ,  C07D231/56 ,  C07D403/10 ,  C07D405/12 ,  C07D417/10 ,  C07D471/04

Abstract: Compounds, compositions and methods are provided for modulating the activity of EP2 and EP4 receptors, and for the treatment, prevention and amelioration of one or more symptoms of diseases or disorders related to the activity of EP2 and EP4 receptors. In certain embodiments, the compounds are antagonists of both the EP2 and EP4 receptors.

公开(公告)号：US20210024491A1

公开(公告)日：2021-01-28

申请号：US17070554

申请日：2020-10-14

Applicant: Tempest Therapeutics, Inc.

Inventor： Yalda BRAVO ,  Austin Chih-Yu CHEN ,  Jinyue DING ,  Robert GOMEZ ,  Heather LAM ,  Joe Fred NAGAMIZO ,  Renata Marcella OBALLA ,  David Andrew POWELL ,  Tao SHENG

IPC: C07D401/10 ,  C07D209/42 ,  C07D405/12 ,  C07D471/04 ,  C07D403/10 ,  C07D417/10 ,  C07D231/56

Abstract: Compounds, compositions and methods are provided for modulating the activity of EP2 and EP4 receptors, and for the treatment, prevention and amelioration of one or more symptoms of diseases or disorders related to the activity of EP2 and EP4 receptors. In certain embodiments, the compounds are antagonists of both the EP2 and EP4 receptors.

公开(公告)号：US20190315712A1

公开(公告)日：2019-10-17

申请号：US16387294

申请日：2019-04-17

Applicant: Tempest Therapeutics, Inc.

Inventor： Yalda BRAVO ,  Austin Chih-Yu CHEN ,  Jinyue DING ,  Robert GOMEZ ,  Heather LAM ,  Joe Fred NAGAMIZO ,  Renata Marcella OBALLA ,  David Andrew POWELL ,  Tao SHENG

IPC: C07D401/10 ,  C07D209/42 ,  C07D405/12 ,  C07D231/56 ,  C07D403/10 ,  C07D417/10 ,  C07D471/04

Abstract: Compounds, compositions and methods are provided for modulating the activity of EP2 and EP4 receptors, and for the treatment, prevention and amelioration of one or more symptoms of diseases or disorders related to the activity of EP2 and EP4 receptors. In certain embodiments, the compounds are antagonists of both the EP2 and EP4 receptors.