公开(公告)号：US20230172886A1

公开(公告)日：2023-06-08

申请号：US17996830

申请日：2021-04-23

Applicant: Temple University-Of The Commonwealth System of Higher Education

Inventor： Salim MERALI ,  Wayne E. CHILDERS ,  Carlos BARRERO ,  George C. MORTON ,  Mario Cesar RICO

IPC: A61K31/198 ,  A61P1/16 ,  A61K9/00

CPC classification number: A61K31/198 ,  A61P1/16 ,  A61K9/0056

Abstract: (S)-2-amino-6-((3-aminopropyl)amino)hexanoic acid (APL) for use in the treatment of non-alcoholic steatohepatitis (NASH), liver inflammation, hepatocellular ballooning, liver fibrosis and steatosis.