公开(公告)号：US20220380534A1

公开(公告)日：2022-12-01

申请号：US17620570

申请日：2020-06-22

Applicant: The Board of Regents of The University of Texas System

Inventor： Jinming GAO ,  Xu WANG ,  Houliang TANG ,  Wei LI ,  Jonathan WILHELM ,  Baran SUMER

IPC: C08G65/333 ,  A61P35/00 ,  A61K9/107 ,  C08G65/334

Abstract: The present disclosure relates to degradable polymers which contain a hydrophobic and hydrophilic segment which is sensitive to pH. In some aspects, the polymers form a micelle which is sensitive to pH and have backbones which are capable of undergoing degradation in vivo. In some aspects, the disclosure also provides methods of using these degradable polymers for the delivery of a drug.