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公开(公告)号：US20150126411A1
公开(公告)日：2015-05-07
申请号：US14534898
申请日：2014-11-06
发明人： Guillermo Garcia-Cardena , Peter Mack , Jeffrey T. Borenstein , Ahmad S. Khalil , Eli J. Weinberg , Jason O. Fiering , Ernest S. Kim , William J. Adams, JR. , Mitchell Hansberry , Stephen Bellio
IPC分类号： B01J19/00
CPC分类号： B01J19/0046 , B01J2219/00587 , C12M23/12 , C12M35/04
摘要： The systems and methods described herein relate to a high-throughput flow apparatus. The apparatus is used with an array of wells, and is configured to impart a predetermined shear stress on cells cultured within each of the wells of the array of wells. The apparatus includes a plurality of mechanical tips. The plurality of mechanical tips each includes a head with a hemispheroid shape. The apparatus also includes a motor associated with at least one of plurality of mechanical tips. The motor is configured to drive the plurality of mechanical tips to impart the shear stress pattern in each of the wells.
摘要翻译： 本文所述的系统和方法涉及高通量流量装置。 该装置与井阵列一起使用，并且被配置为对孔阵列的每个孔内的细胞施加预定的剪切应力。 该装置包括多个机械末端。 多个机械末端各自包括具有半球形形状的头部。 该装置还包括与多个机械末端中的至少一个相关联的马达。 马达被配置为驱动多个机械末端以赋予每个孔中的剪切应力模式。
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公开(公告)号：US10232336B2
公开(公告)日：2019-03-19
申请号：US14534898
申请日：2014-11-06
发明人： Guillermo Garcia-Cardena , Peter Mack , Jeffrey T. Borenstein , Ahmad S. Khalil , Eli J. Weinberg , Jason O. Fiering , Ernest S. Kim , William J. Adams, Jr. , Mitchell Hansberry , Stephen Bellio
摘要： The systems and methods described herein relate to a high-throughput flow apparatus. The apparatus is used with an array of wells, and is configured to impart a predetermined shear stress on cells cultured within each of the wells of the array of wells. The apparatus includes a plurality of mechanical tips. The plurality of mechanical tips each includes a head with a hemispheroid shape. The apparatus also includes a motor associated with at least one of plurality of mechanical tips. The motor is configured to drive the plurality of mechanical tips to impart the shear stress pattern in each of the wells.
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公开(公告)号：US10101496B2
公开(公告)日：2018-10-16
申请号：US15379468
申请日：2016-12-14
摘要： A system and method of injection well identification using tracer particles is disclosed. A collector-reader for analyzing magnetic particles in a fluid that is moving with respect to the collector-reader includes an array of magnets whose magnetization direction is varied so as to create regions of high magnetic field gradient in the fluid, a stopper configured to concentrate spatially the particles attracted to the array, and a reader including a source configured to excite the particles concentrated by the stopper and a detector configured to capture a particle excitation signature emitted by the magnetic particles. A method for observing a subterranean reservoir penetrated by a production well and two or more injection wells is also disclosed.
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公开(公告)号：US20170097443A1
公开(公告)日：2017-04-06
申请号：US15379468
申请日：2016-12-14
CPC分类号： G01V15/00 , E21B43/16 , E21B47/1015 , G01N23/223 , G01N33/2882 , G01V5/125
摘要： A system and method of injection well identification using tracer particles is disclosed. A collector-reader for analyzing magnetic particles in a fluid that is moving with respect to the collector-reader includes an array of magnets whose magnetization direction is varied so as to create regions of high magnetic field gradient in the fluid, a stopper configured to concentrate spatially the particles attracted to the array, and a reader including a source configured to excite the particles concentrated by the stopper and a detector configured to capture a particle excitation signature emitted by the magnetic particles. A method for observing a subterranean reservoir penetrated by a production well and two or more injection wells is also disclosed.
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