-
公开(公告)号:US20220257653A1
公开(公告)日:2022-08-18
申请号:US17597580
申请日:2020-07-17
申请人: The Children's Hospital of Philadelphia , THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVIC , THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
发明人: Kristopher BOSSE , John MARIS , David BARRETT , Jessica FOSTER , Dimiter DIMITROV , Crystal MACKALL , Robbie MAJZNER , ZHONGYU ZHU , Sabine HEITZENEDER , Dontcho V. JELEV
IPC分类号: A61K35/17 , C07K14/725 , C07K16/30 , C07K14/705 , A61P35/00
摘要: The present disclosure is directed to chimeric antigen receptors binding to Glypican 2, nucleic acids encoding the same, and cells expressing the same, and methods of using such cells to treat cancers that express or overexpress the Glypican 2 antigen.