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公开(公告)号:US20180134763A1
公开(公告)日:2018-05-17
申请号:US15705789
申请日:2017-09-15
发明人: Jack JHAMANDAS , Rania SOUDY , Kamaljit KAUR , Wen FU , David MacTAVISH , Aarti PATEL
IPC分类号: C07K14/575 , A61P25/28
CPC分类号: C07K14/575 , A61K38/00 , A61P25/28 , C07K14/585
摘要: Amylin receptor antagonists capable of binding to the amylin receptor and inhibiting activity of amylin or amyloid-beta protein are provided. The amylin receptor antagonists can be administered in the form of pharmaceutical compositions or the like. Methods for preparing and using the amylin receptor antagonists for treating, preventing, or ameliorating Alzheimer's disease are also provided.