公开(公告)号：US20230066806A1

公开(公告)日：2023-03-02

申请号：US17439328

申请日：2020-03-13

Applicant: The Regents of the University of California

Inventor： Theodore Lee Roth ,  Po-Yi Jonathan Li ,  Alexander Marson ,  Jasper Nies ,  Cody Mowery ,  Eric Shifrut ,  Franziska Blaeschke ,  Ryan Apathy

IPC: C12N15/10 ,  C12N15/90 ,  A61K35/17 ,  A61P35/00 ,  A61P17/00

Abstract: Provided herein are methods and compositions for identifying a targeted genomic insertion in a cell. Also provided are heterologous polypeptides that are co-expressed under the control of enodogenous loci and methods of using same.