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公开(公告)号:US20240041994A1
公开(公告)日:2024-02-08
申请号:US18311557
申请日:2023-05-03
申请人: The Regents of the University of California , The Board of Regents of the University of Oklahoma
IPC分类号: A61K39/00 , A61K39/395 , A61K39/12 , C07K14/74
CPC分类号: A61K39/0005 , A61K39/3955 , A61K39/12 , C07K14/70539 , A61K2039/505 , A61K2039/572 , A61K2039/58
摘要: The present invention provides vaccine compositions for preventing and/or treating cytomegalovirus (CMV) infection and methods of making and using the same.
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公开(公告)号:US20160311906A1
公开(公告)日:2016-10-27
申请号:US15081305
申请日:2016-03-25
CPC分类号: C07K16/2851 , A61K2039/505 , C07K2317/24 , C07K2317/76 , C07K2317/77 , G01N33/5047
摘要: The present invention relates to methods and compositions for treating and/or preventing inflammation associated with viral infection and solid organ transplant rejection. In particular, the present invention provides therapeutics for impairing the expansion and function of autoreactive T cells, NK cells and/or NKT cells, by modulating NKG2D.
摘要翻译: 本发明涉及用于治疗和/或预防与病毒感染和实体器官移植排斥相关的炎症的方法和组合物。 特别地,本发明提供了通过调节NKG2D来损害自身反应性T细胞,NK细胞和/或NKT细胞的扩增和功能的治疗剂。
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公开(公告)号:US20140120082A1
公开(公告)日:2014-05-01
申请号:US13797921
申请日:2013-03-12
IPC分类号: A61K39/395
CPC分类号: A61K39/39541 , A61K2039/505 , C07K16/2851 , C07K2316/96 , C07K2317/73 , C07K2317/76 , Y10S514/885
摘要: The present invention relates to methods and compositions for treating and/or preventing autoimmune and/or inflammatory disease. In particular, the present invention provides therapeutics for impairing the expansion and function of autoreactive T cells, NK cells and/or NKT cells, by modulating NKG2D.
摘要翻译: 本发明涉及用于治疗和/或预防自身免疫和/或炎性疾病的方法和组合物。 特别地,本发明提供了通过调节NKG2D来损害自身反应性T细胞,NK细胞和/或NKT细胞的扩增和功能的治疗剂。
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