公开(公告)号：US20230110354A1

公开(公告)日：2023-04-13

申请号：US18075627

申请日：2022-12-06

申请人： The Regents of the University of Colorado, a Body Corporate

发明人： Jessica Anne Yu Rove ,  Dae Won Park ,  Adam J. Rocker

IPC分类号： A61K31/167 ,  A61K9/51 ,  A61L29/14

摘要： A novel therapeutic agent delivery system, methods of use and methods of formation thereof are presented. The novel delivery system is comprised of novel nanoparticles capable of at least partially encapsulating a therapeutic agent such as an anesthetic, antimicrobial, growth factor or protein. The nanoparticles are embedded with in a crosslinked hydrogel. The hydrogel can be administered directly to a patient or may be coated onto a device such as a catheter. The delivery system allows for a sustained release of the therapeutic agent over an extended period of time.