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公开(公告)号:US20230233517A1
公开(公告)日:2023-07-27
申请号:US17852475
申请日:2022-06-29
发明人: Ding Xue , Yu Peng , Man Zhang , Lingjun Zheng , Qian Liang , Hanzeng Li , Jau-Song Yu , Jeng-Ting Chen
IPC分类号: A61K31/353 , A61K31/336 , A61K31/4025 , A61K31/7048
CPC分类号: A61K31/353 , A61K31/336 , A61K31/4025 , A61K31/7048
摘要: The invention provides novel compositions and methods for the treatment of Radiation-Induced Bystander Effects (RIBE), resulting from radiation exposure. In one preferred embodiment the inventions includes novel therapeutic agents, including but not limited to quercetin and quercetin analogs, as well as E64, CA074, CA074Me, that interfere with the activity of Cathepsin B.