专利检索 ap:("The Regents of the University of Michigan") AND inv:"Kun-Liang Guan" 第 1 页

1.

发明申请
Diagnosis and treatment of diseases arising from defects in the tuberous sclerosis pathway 有权
标题翻译：诊断和治疗结节性硬化症途径缺陷引起的疾病

公开(公告)号：US20040106637A1

公开(公告)日：2004-06-03

申请号：US10639263

申请日：2003-08-12

申请人： The Regents of the University of Michigan

发明人： Kun-Liang Guan

IPC分类号： A61K031/4745 , G01N033/53 , G01N033/537 , G01N033/543 , C12Q001/48

CPC分类号： G01N33/5041 , C12Q1/485

摘要： The present invention relates to compositions and methods for identifying abnormalities in TSC signaling pathways. In particular, the present invention relates to methods of diagnosing and treating disorders such as tuberous sclerosis, which are caused by mutations in the TSC genes. The present invention further relates to methods and compositions for treating cancers mediated by TSC signaling disorders.

摘要翻译： 本发明涉及鉴定TSC信号通路异常的组合物和方法。特别地，本发明涉及诊断和治疗由TSC基因突变引起的结节性硬化症等疾病的方法。本发明还涉及用于治疗由TSC信号传导疾病介导的癌症的方法和组合物。