专利检索 ap:("The Regents of the University of Michigan") AND inv:"Y. Eugene Chen" 第 1 页

1.

发明公开
ITACONATE AND DERIVATIVES THEREOF FOR THE PROTECTION OF CELLS, TISSUES, AND ORGANS 审中-公开

公开(公告)号：US20240341301A1

公开(公告)日：2024-10-17

申请号：US18627185

申请日：2024-04-04

申请人： The Regents of the University of Michigan

发明人： Paul C. TANG , Y. Eugene Chen , Lenglam Lei

IPC分类号： A01N1/02

CPC分类号： A01N1/0226

摘要： Provided herein are pharmaceutical compositions and tissue/organ preservation solutions comprising itaconate and/or derivatives thereof and methods of use thereof. In particular, provided herein are compositions comprising itaconate and methods of use thereof for the preservation of tissues/organs for transplantation and treatment/prevention/reduction of conditions such as myocardial infarction, sudden cardiac arrest, stroke, senescence, cardiomyopathies, and cardiotoxicity.