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公开(公告)号:US11639930B2
公开(公告)日:2023-05-02
申请号:US16761034
申请日:2018-11-01
申请人: The U.S.A., as represented by the Secretary, Department of Health and Human Services , Yale University
发明人: Sanjai Kumar , Nitin Verma , Ankit Puri , Peter J. Krause
IPC分类号: C07K14/44 , G01N33/543 , C12N15/10 , G01N33/569
摘要: Identification of immunodominant Babesia microti antigens using genome-wide immunoscreening is described. Candidate antigens were screened against sera from patients with clinical babesiosis. Also described are diagnostic assays with high sensitivity and specificity for detecting B. microti-specific antibodies in patient samples using the identified immunodominant antigens.
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公开(公告)号:US20210181190A1
公开(公告)日:2021-06-17
申请号:US16761034
申请日:2018-11-01
申请人: The U.S.A., as represented by the Secretary, Department of Health and Human Services , Yale University
发明人: Sanjai Kumar , Nitin Verma , Ankit Puri , Peter J. Krause
IPC分类号: G01N33/543 , C12N15/10 , C07K14/44 , G01N33/569
摘要: Identification of immunodominant Babesia microti antigens using genome-wide immunoscreening is described. Candidate antigens were screened against sera from patients with clinical babesiosis. Also described are diagnostic assays with high sensitivity and specificity for detecting B. microti-specific antibodies in patient samples using the identified immunodominant antigens.
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3.
公开(公告)号:US20230266306A1
公开(公告)日:2023-08-24
申请号:US18187241
申请日:2023-03-21
发明人: Sanjai Kumar , Nitin Verma , Ankit Puri
IPC分类号: G01N33/543 , C07K14/44 , C12N15/10 , G01N33/569
CPC分类号: G01N33/54306 , C07K14/44 , C12N15/1096 , G01N33/56905 , C07K2319/00 , G01N2469/20
摘要: Identification of immunodominant Babesia microti antigens using genome-wide immunoscreening is described. Candidate antigens were screened against sera from patients with clinical babesiosis. Also described are diagnostic assays with high sensitivity and specificity for detecting B. microti-specific antibodies in patient samples using the identified immunodominant antigens.
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