专利检索 ap:("The United States of America, as represented by the Secretary of Agriculture") AND inv:"ROBERT E BRIGGS" 第 1 页

1.

发明申请
NOVEL PASTEURELLA MULTOCIDA STRAINS AND VACCINES HAVING HYAC AND NANP DELETIONS 有权

公开(公告)号：US20220098558A1

公开(公告)日：2022-03-31

申请号：US17478023

申请日：2021-09-17

申请人： The United States of America, as represented by the Secretary of Agriculture

发明人： ROBERT E BRIGGS , FRED M TATUM

IPC分类号： C12N9/04 , C12N9/16 , A61K39/102

摘要： The present invention provides novel attenuated Pasteurella multocida strains that may be used, in live or killed form, to formulate vaccines that are highly protective against P. multocida infection in bovines, other mammals, and in birds. The present invention also identifies the combination of nanP and hyaC gene mutations as key to the provision of such vaccines. When appropriately formulated, antigenic material of numerous other bovine pathogens may be combined with the live attenuated Pasteurella multocida strains, to make effective combination vaccines.

2.

发明申请
SOUTHERN CATTLE TICK VACCINE PRODUCT 有权

公开(公告)号：US20210275648A1

公开(公告)日：2021-09-09

申请号：US17190235

申请日：2021-03-02

申请人： The United States of America, as represented by the Secretary of Agriculture

发明人： ADALBERTO A PEREZ DE LEON , ROBERT E BRIGGS , FRED M TATUM , Robert Miller , Felicito Guerrero

IPC分类号： A61K39/00 , C07K14/33 , C07K14/435 , A61K39/08 , A61P33/14

摘要： This invention relates to novel fusion peptides and immunogenic compositions containing the fusion peptides useful in the control and prevention of tick infestations. The invention also relates to compositions comprising said fusion peptides, methods of vaccination against tick infestation using said fusion peptides and compositions, and kits for use with such compositions and methods.

3.

发明申请
MANNHEIMIA HAEMOLYTICA VECTOR AND MYCOPLASMA BOVIS VACCINE PRODUCT 有权

公开(公告)号：US20210275660A1

公开(公告)日：2021-09-09

申请号：US17190182

申请日：2021-03-02

申请人： The United States of America, as represented by the Secretary of Agriculture

发明人： ROBERT E BRIGGS , FRED M TATUM

IPC分类号： A61K39/102 , A61K39/04 , A61P31/04

摘要： The present invention relates to modified Mannheimia haemolytica (M. haemolytica) lktCA gene cluster cassettes, compositions comprising such cassettes, methods of using such cassettes and compositions, and kits comprising such cassettes and compositions. Also described herein are Mycoplasma bovis (M. bovis) protective antigens, compositions comprising such antigens, methods of using such antigens and compositions, and kits comprising such antigens and compositions. Also described herein are modified M. haemolytica lktCA gene cluster cassettes engineered to express M. bovis protective antigens, compositions comprising such cassettes, methods of using such cassettes and compositions, and kits comprising such cassettes and compositions.