专利检索 ap:("The University of North Carolina at Chapel Hill") AND inv:"Duhyeong HWANG" 第 1 页

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发明申请
DRUG DELIVERY COMPOSITIONS AND APPLICATIONS THEREOF 有权

公开(公告)号：US20220356287A1

公开(公告)日：2022-11-10

申请号：US17620800

申请日：2020-06-19

申请人： The University of North Carolina at Chapel Hill

发明人： Alexander KABANOV , Duhyeong HWANG , Marina SOKOLSKY

IPC分类号： C08F277/00 , A61K47/34 , C08F20/54 , A61K9/107

摘要： In one aspect, amphiphilic block copolymers are described herein comprising a first block and a second block, the second block including monomer having a side chain comprising a heteroaryl moiety, wherein the second block is more hydrophobic than the first block. In some embodiments, the heteroaryl moiety is a five-membered ring or six membered ring. Amphiphilic block copolymers described herein, in some embodiments, can be used to form micellar compositions for solubilizing and delivering water insoluble pharmaceutical and/or therapeutic agents.