METHOD FOR PROVIDING NEUROPROTECTION FROM SPINAL MUSCULAR ATROPHY
    1.
    发明申请
    METHOD FOR PROVIDING NEUROPROTECTION FROM SPINAL MUSCULAR ATROPHY 有权
    用于向脊柱肌瘤提供神经保护的方法

    公开(公告)号:US20120316141A1

    公开(公告)日:2012-12-13

    申请号:US13591789

    申请日:2012-08-22

    IPC分类号: A61K31/575 A61P25/00

    CPC分类号: C07J9/00 A61K31/575

    摘要: A method for providing neuroprotection to a patient in need of neuroprotection, comprising administering a neuroprotective-effective amount of a compound of formula I in which X is an oxygen atom or an ═N—OH group, R is selected from the group consisting of A is a hydrogen atom or together with B a carbon-carbon bond, B is a hydrogen atom, a hydroxy group or together with A a carbon-carbon bond, C is a hydrogen atom or together with D a carbon-carbon bond, D is a hydrogen atom or together with C a carbon-carbon bond, E is a hydrogen atom or together with F a carbon-carbon bond, F is a hydrogen atom or together with E a carbon-carbon bond, or an addition salt with a pharmaceutically acceptable acid.

    摘要翻译: 一种向需要神经保护的患者提供神经保护的方法,包括给予神经保护有效量的其中X为氧原子或= N-OH基团的式I化合物,R选自A 是氢原子或与B一起形成碳 - 碳键,B为氢原子,羟基或与A为碳 - 碳键,C为氢原子,或与D为碳 - 碳键,D为 氢原子或与碳碳键一起,E为氢原子,或与F为碳 - 碳键,F为氢原子,或与碳为碳原子一起形成,或与药物上的加成盐 可接受的酸。

    USE AS MEDICAMENTS OF DERIVATIVES OF CHOLEST-4-EN-3-ONE, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, NOVEL DERIVATIVES AND THEIR PREPARATION PROCESS
    2.
    发明申请
    USE AS MEDICAMENTS OF DERIVATIVES OF CHOLEST-4-EN-3-ONE, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, NOVEL DERIVATIVES AND THEIR PREPARATION PROCESS 有权
    用作美洛昔康4-EN-3-ONE衍生物的药物,含有它们的药物组合物,新型衍生物及其制备方法

    公开(公告)号:US20100216752A1

    公开(公告)日:2010-08-26

    申请号:US12776217

    申请日:2010-05-07

    CPC分类号: C07J9/00 A61K31/575

    摘要: A method for providing neuroprotection to a patient in need of neuroprotection, comprising administering a neuroprotective-effective amount of a compound of formula I in which X is an oxygen atom or an ═N—OH group, R is selected from the group consisting of A is a hydrogen atom or together with B a carbon-carbon bond, B is a hydrogen atom, a hydroxy group or together with A a carbon-carbon bond, C is a hydrogen atom or together with D a carbon-carbon bond, D is a hydrogen atom or together with C a carbon-carbon bond, E is a hydrogen atom or together with F a carbon-carbon bond, F is a hydrogen atom or together with E a carbon-carbon bond, or an addition salt with a pharmaceutically acceptable acid.

    摘要翻译: 一种向需要神经保护的患者提供神经保护的方法,包括给予神经保护有效量的其中X为氧原子或= N-OH基团的式I化合物,R选自A 是氢原子或与B一起形成碳 - 碳键,B为氢原子,羟基或与A为碳 - 碳键,C为氢原子,或与D为碳 - 碳键,D为 氢原子或与碳碳键一起,E为氢原子,或与F为碳 - 碳键,F为氢原子,或与碳为碳原子一起形成,或与药物上的加成盐 可接受的酸。