公开(公告)号：US09944948B2

公开(公告)日：2018-04-17

申请号：US13881792

申请日：2011-10-27

申请人： Thierry Bogaert ,  Romaan Raemaekers ,  Yann Naudet

发明人： Thierry Bogaert ,  Romaan Raemaekers ,  Yann Naudet

IPC分类号： C12N15/82 ,  C12N15/113

CPC分类号： C12N15/8286 ,  C12N15/113 ,  C12N2310/14 ,  C12N2310/51 ,  C12N2310/531 ,  C12N2330/51

摘要： The present invention relates to the prevention and/or control of infestation by insect pest species. In particular, the invention relates to down-regulation of expression of target genes in insect pests using interfering ribonucleic acid (RNA) molecules. Also described are transgenic plants that (i) express or are capable of expressing interfering RNAs of the invention and (ii) are resistant to infestation by insect pest species. Compositions containing the interfering RNAs of the invention are also provided.

公开(公告)号：US20130291188A1

公开(公告)日：2013-10-31

申请号：US13881792

申请日：2011-10-27

申请人： Thierry Bogaert ,  Romaan Raemaekers ,  Yann Naudet

发明人： Thierry Bogaert ,  Romaan Raemaekers ,  Yann Naudet

IPC分类号： C12N15/82

CPC分类号： C12N15/8286 ,  C12N15/113 ,  C12N2310/14 ,  C12N2310/51 ,  C12N2310/531 ,  C12N2330/51

摘要： The present invention relates to the prevention and/or control of infestation by insect pest species. In particular, the invention relates to down-regulation of expression of target genes in insect pests using interfering ribonucleic acid (RNA) molecules. Also described are transgenic plants that (i) express or are capable of expressing interfering RNAs of the invention and (ii) are resistant to infestation by insect pest species. Compositions containing the interfering RNAs of the invention are also provided.

摘要翻译： 本发明涉及防治和/或防治害虫物种侵染。 特别地，本发明涉及使用干扰核糖核酸（RNA）分子对害虫中靶基因表达的下调。 还描述了（i）表达或能够表达本发明的干扰RNA的转基因植物，和（ii）对昆虫害虫侵染的抗性。 还提供了含有本发明的干扰RNA的组合物。

公开(公告)号：US20120258929A1

公开(公告)日：2012-10-11

申请号：US11993586

申请日：2006-06-23

申请人： Yasutaka Shimokawatoko ,  Marc Van De Craen ,  Irene Nooren ,  Sandra Turconi ,  Yann Naudet ,  Guy Nys ,  Jurgen Debaveye

发明人： Yasutaka Shimokawatoko ,  Marc Van De Craen ,  Irene Nooren ,  Sandra Turconi ,  Yann Naudet ,  Guy Nys ,  Jurgen Debaveye

IPC分类号： A01N43/08 ,  A01N43/36 ,  C07D285/135 ,  A01N43/824 ,  C07D225/06 ,  A01N43/46 ,  C07J1/00 ,  A01N45/00 ,  C07D209/52 ,  A01N43/38 ,  C07D217/26 ,  A01N43/42 ,  C07H19/067 ,  C07D277/54 ,  A01N43/78 ,  A01P7/04 ,  C12N15/57 ,  C12Q1/37 ,  C12N9/48 ,  C12Q1/68 ,  C12N15/66 ,  C12N5/10 ,  C12N15/64 ,  C12N7/01 ,  C07D207/16

CPC分类号： A01N61/00 ,  A01N43/36 ,  A01N43/38 ,  A01N43/42 ,  A01N43/46 ,  A01N45/00 ,  A01N47/36 ,  A01N63/00 ,  C07J41/0038 ,  C12N9/485 ,  C12N9/6402 ,  C12N9/99 ,  C12N2799/026 ,  C12Q1/37 ,  C12Y304/15001 ,  G01N2500/04

摘要： The present invention provides an agent that modulates physiological condition of pests, wherein the agent has an ability to modulate the activity of an insect peptidyl-dipeptidase A; a method for assaying pesticidal activity of a test substance, which comprises a step of measuring the activity of a peptidyl-dipeptidase A in a reaction system in which the peptidyl-dipeptidase A contacts with a test substance, and the like.

摘要翻译： 本发明提供了调节害虫生理状态的试剂，其中该试剂具有调节昆虫肽基二肽酶A活性的能力; 用于测定被检物质的杀虫活性的方法，其包括测定肽基 - 二肽酶A与检测物质接触的反应体系中肽基二肽酶A的活性的步骤等。