Affinity Measurements Using Frameless Multiplexed Microarrays
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    发明申请
    Affinity Measurements Using Frameless Multiplexed Microarrays 审中-公开
    使用无框复用微阵列的亲和度测量

    公开(公告)号:US20090111709A1

    公开(公告)日:2009-04-30

    申请号:US12260537

    申请日:2008-10-29

    IPC分类号: C40B30/04

    CPC分类号: C40B30/04 G01N33/6845

    摘要: The present invention relates to novel methods of the quantitative detection of molecules in an array. In particular, the present invention relates to methods for molecular detection assays performed on solid surfaces. The present invention provides improved methods for the high throughput analysis of molecular interactions and quantitative detection. In another aspect, the invention relates to a method of measuring protein interactions on a solid surface that is useful for the determination of equilibrium binding and rate constants. In yet another aspect, the invention relates to predicting a molecules utility in a detection assay.

    摘要翻译: 本发明涉及定量检测阵列中分子的新方法。 特别地,本发明涉及在固体表面上进行的分子检测测定方法。 本发明提供了用于分子相互作用和定量检测的高通量分析的改进方法。 在另一方面,本发明涉及测量固体表面上的蛋白质相互作用的方法,其用于测定平衡结合和速率常数。 在另一方面,本发明涉及在检测测定中预测分子效用。