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公开(公告)号：US08333773B2
公开(公告)日：2012-12-18
申请号：US11847488
申请日：2007-08-30
IPC分类号： A61B17/58
CPC分类号： A61B17/8822 , A61F2/4601 , A61F2002/3008 , A61F2002/30523 , A61F2002/48 , A61F2220/0025 , A61F2250/0098
摘要： A remotely-activated injection device for use in vertebroplasty is provided to inject a flourescent probe material into a patient. The injection device includes a pump defining an injection chamber having an exit opening; an actuator; and a cable having a first end coupled to the actuator, and a second end remotely engaging the pump. The actuator remotely controls the pump by responsive movement of the cable to thereby cause injection of a flourescent probe material from the injection chamber of the pump through the exit opening to the patient.
摘要翻译： 提供用于椎体成形术的远程激活的注射装置以将荧光探针材料注射到患者体内。 注射装置包括限定具有出口的注射室的泵; 执行机构 以及电缆，其具有联接到所述致动器的第一端，以及远离所述泵的第二端。 致动器通过电缆的响应运动远程地控制泵，从而使得荧光探针材料从泵的注射室通过出口向患者注入。
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公开(公告)号：US20090270872A1
公开(公告)日：2009-10-29
申请号：US12388563
申请日：2009-02-19
CPC分类号： A61B17/8822 , A61F2/4601 , A61F2002/3008 , A61F2002/30523 , A61F2002/48 , A61F2220/0025 , A61F2250/0098
摘要： A remotely-activated injection device for use in vertebroplasty is provided to inject a flourescent probe material into a patient. The injection device includes a pump defining an injection chamber having an exit opening; an actuator; and a cable having a first end coupled to the actuator, and a second end remotely engaging the pump. The actuator remotely controls the pump by responsive movement of the cable to thereby cause injection of a flourescent probe material from the injection chamber of the pump through the exit opening to the patient.
摘要翻译： 提供用于椎体成形术的远程激活的注射装置以将荧光探针材料注射到患者体内。 注射装置包括限定具有出口的注射室的泵; 执行机构 以及电缆，其具有联接到所述致动器的第一端，以及远离所述泵的第二端。 致动器通过电缆的响应运动远程地控制泵，从而使得荧光探针材料从泵的注射室通过出口向患者注入。
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公开(公告)号：US09839460B2
公开(公告)日：2017-12-12
申请号：US12388563
申请日：2009-02-19
CPC分类号： A61B17/8822 , A61F2/4601 , A61F2002/3008 , A61F2002/30523 , A61F2002/48 , A61F2220/0025 , A61F2250/0098
摘要： A remotely-activated injection device for use in vertebroplasty is provided to inject a flourescent probe material into a patient. The injection device includes a pump defining an injection chamber having an exit opening; an actuator; and a cable having a first end coupled to the actuator, and a second end remotely engaging the pump. The actuator remotely controls the pump by responsive movement of the cable to thereby cause injection of a flourescent probe material from the injection chamber of the pump through the exit opening to the patient.
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4.发明授权Trans-capsular administration of high specificity cytokine inhibitors into orthopedic joints 有权将高特异性细胞因子抑制剂的跨荚膜施用于矫形关节公开(公告)号：US08361467B2
公开(公告)日：2013-01-29
申请号：US10630227
申请日：2003-07-30
申请人： Thomas M. DiMauro , Mohamed Attawia , Hassan Serhan , Martin A. Reynolds , Melissa Grace , Sudhakar Kadiyala , David Urbahns , Scott Bruder , Gregory Collins , Laura J. Brown , Jeff Geesin , Pamela L. Plouhar , Catherine Smith , John Siekierka
发明人： Thomas M. DiMauro , Mohamed Attawia , Hassan Serhan , Martin A. Reynolds , Melissa Grace , Sudhakar Kadiyala , David Urbahns , Scott Bruder , Gregory Collins , Laura J. Brown , Jeff Geesin , Pamela L. Plouhar , Catherine Smith , John Siekierka
IPC分类号： A61K39/395 , A61K39/00 , A61K38/18
CPC分类号： A61K38/30 , A61K31/198 , A61K31/436 , A61K38/1816 , A61K2039/505
摘要： The present invention relates to trans-capsularly administering into a diseased joint a high specificity antagonist selected from the group consisting of: i) an inhibitor of a pro-inflammatory interleukin; ii) an inhibitor of TNF-α synthesis; iii) an inhibitor of membrane-bound TNF-α; iv) an inhibitor of a natural receptor of TNF-α; v) an inhibitor of NO synthase, vi) an inhibitor of PLA2 enzyme; vii) an anti-proliferative agent; viii) an anti-oxidant; ix) an apoptosis inhibitor selected from the group consisting of EPO mimetic peptides, EPO mimetibodies, IGF-I, IGF-II, and caspase inhibitors, and x) an inhibitor of MMPs; and xi) an inhibitor of p38 kinase.
摘要翻译： 本发明涉及向患病关节中透射施用高特异性拮抗剂，所述高特异性拮抗剂选自：i）促炎白细胞介素的抑制剂; ii）TNF-α合成抑制剂; iii）膜结合TNF-α的抑制剂; iv）TNF-α的天然受体的抑制剂; v）NO合酶抑制剂，vi）PLA2酶抑制剂; vii）抗增殖剂; viii）抗氧化剂; ix）选自EPO模拟肽，EPO模拟物，IGF-I，IGF-II和胱天蛋白酶抑制剂的细胞凋亡抑制剂，和x）MMP的抑制剂; 和xi）p38激酶的抑制剂。
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5.发明授权公开(公告)号：US06827716B2
公开(公告)日：2004-12-07
申请号：US10261215
申请日：2002-09-30
IPC分类号： A61B1818
CPC分类号： A61B18/1492 , A61B2017/00057 , A61B2017/00261 , A61B2018/0044 , A61N7/02
摘要： This invention relates to a method of treating an intervertebral disc comprising locally identifying a pathologic tissue site and therapeutically treating the identified site.
摘要翻译： 本发明涉及一种治疗椎间盘的方法，其包括局部鉴定病理组织部位并治疗所述鉴定部位。
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6.发明授权公开(公告)号：US07811321B2
公开(公告)日：2010-10-12
申请号：US11207356
申请日：2005-08-18
申请人： Martin A. Reynolds
发明人： Martin A. Reynolds
IPC分类号： A61F2/44
CPC分类号： A61B17/8822 , A61B2017/564
摘要： This invention relates to improved vertebroplasty procedures for reducing embolisms, leakage and cement loosening.
摘要翻译： 本发明涉及用于减少栓塞，渗漏和水泥松动的改进的椎体成形术程序。
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公开(公告)号：US20090248076A1
公开(公告)日：2009-10-01
申请号：US12055757
申请日：2008-03-26
CPC分类号： A61B17/7062
摘要： An interspinous spacer having a pair of hooks that, upon lateral insertion between opposed spinous process, bear upon the opposed spinous processes.
摘要翻译： 棘突间隔物具有一对钩，当在相对的棘突之间横向插入时，它们承受相对的棘突。
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8.发明授权公开(公告)号：US06979352B2
公开(公告)日：2005-12-27
申请号：US10301451
申请日：2002-11-21
申请人： Martin A. Reynolds
发明人： Martin A. Reynolds
CPC分类号： A61B17/8822 , A61B2017/564
摘要： This invention relates to improved vertebroplasty procedures for reducing embolisms, leakage and cement loosening.
摘要翻译： 本发明涉及用于减少栓塞，渗漏和水泥松动的改进的椎体成形术程序。
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公开(公告)号：US08313512B2
公开(公告)日：2012-11-20
申请号：US12239631
申请日：2008-09-26
申请人： Seungkyu Daniel Kwak , Mark Gracia , John Riley Hawkins , Lisa Gilman , John Griffin , Martin A. Reynolds , Hassan Serhan
发明人： Seungkyu Daniel Kwak , Mark Gracia , John Riley Hawkins , Lisa Gilman , John Griffin , Martin A. Reynolds , Hassan Serhan
IPC分类号： A61B17/70
CPC分类号： A61B17/7062 , A61B17/7053 , A61B17/7065
摘要： An S-shaped interspinous spacer having a pair of hooks that, upon lateral insertion between opposed spinous process, bear upon the opposed spinous processes.
摘要翻译： 具有一对钩的S形棘突间间隔物，其在相对的棘突之间横向插入时承受相对的棘突。
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公开(公告)号：US06547790B2
公开(公告)日：2003-04-15
申请号：US09836445
申请日：2001-04-17
申请人： Haynes Louis Harkey, III , Bradford Currier , David M. Selvitelli , Martin A. Reynolds , Thomas V. Doherty
发明人： Haynes Louis Harkey, III , Bradford Currier , David M. Selvitelli , Martin A. Reynolds , Thomas V. Doherty
IPC分类号： A61B1756
CPC分类号： A61B17/7053 , A61B17/7044 , A61B17/7055
摘要： An orthopaedic method and anchor assemblies for anchoring a linkage such as a rod or cable used for fixation or reduction. One assembly includes an anchor plate and a slotted anchor bolt that captures the plate in a one-piece assembly for convenient installation. The base of the anchor bolt lies below the plate, and a cap or nut tightens down to secure a linking member, e.g., a rod or cable, in the slot, simultaneously clamping the bolt to fix both its position and its orientation on the plate. One occipital plate has lateral arms that hold the anchor bolts, and a Y-shaped embodiment is mounted in an inverted orientation to position the anchor bolts well down in soft tissue for more effective wound closure. A cable connector is used together with an anchor plate, vertebra anchor screws and fixation rods to secure ends of a cable at the level of one or more vertebrae, providing a versatile and highly stable system for alignment, fixation and fusing of the cervical and thoracic spine. The cable connectors have an open-sided channel that fits onto and securely clamps to an already-positioned fixation rod, with an eyelet or other structure providing a rigid and fixed securing point for a cable that is threaded about the vertebrae under tension. Methods of fixation are described.
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