公开(公告)号：US06313347B1

公开(公告)日：2001-11-06

申请号：US09744246

申请日：2001-01-30

申请人： Thomas Preiss ,  Jochem Henkelmann ,  Boris Trofimov ,  Albina Mikhaleva ,  Alexander M. Vasiltsov

发明人： Thomas Preiss ,  Jochem Henkelmann ,  Boris Trofimov ,  Albina Mikhaleva ,  Alexander M. Vasiltsov

IPC分类号： C07C24900

CPC分类号： C07C251/38 ,  C07C251/44

摘要： In the process for the preparation of vinyloxime ethers of the formula I by reacting an oxime with an alkyne where R1 and R2 are identical or different and are alkyl or aryl radicals, R3 is hydrogen, an alkyl or aryl radical, and R4 is a radical having the meaning of R3, which may be different than R3, or is a hydroxyalkyl radical, in a superbasic polar organic solvent in the presence of a strong base, the reaction is carried out under conditions such that the resulting vinyloxime ether stays in contact with the other constituents of the reaction mixture for only a short time so that it is unable to decompose or react to give secondary products to a significant extent.

摘要翻译： 在制备式I的乙烯基肟醚的方法中，通过使肟与炔烃反应，R 1和R 2相同或不同，并且是烷基或芳基，R 3是氢，烷基或芳基，R 4是具有 R 3可以不同于R 3，或者是羟烷基，在强碱存在的情况下，在超碱性极性有机溶剂中，该反应在使得所得维琳肟醚与其它成分接触的条件下进行 反应混合物只需很短的时间，使其不能在很大程度上分解或反应得到二次产物。