专利检索 ap:("Thomas R. Simpson" OR "Michael Balestra" OR "Dean G. Brown" OR "Cathy L. Dantzman" OR "Glen E. Ernst" OR "William Frietze" OR "Christopher R. Holmquist" OR "James Kang" OR "Frances M. McLaren" OR "Reed W. Smith, JR." OR "James M. Woods") AND inv:"Christopher R. Holmquist" 第 1 页

1.

发明申请
Thiophene-2-Carboxamide Derivatives as Alpha 7 Nicotinic Receptor Modulators 审中-公开
标题翻译：噻吩-2-甲酰胺衍生物作为α7烟碱受体调节剂

公开(公告)号：US20090012127A1

公开(公告)日：2009-01-08

申请号：US11917818

申请日：2006-06-26

申请人： Thomas R. Simpson , Michael Balestra , Dean G. Brown , Cathy L. Dantzman , Glen E. Ernst , William Frietze , Christopher R. Holmquist , James Kang , Frances M. McLaren , Reed W. Smith, JR. , James M. Woods

发明人： Thomas R. Simpson , Michael Balestra , Dean G. Brown , Cathy L. Dantzman , Glen E. Ernst , William Frietze , Christopher R. Holmquist , James Kang , Frances M. McLaren , Reed W. Smith, JR. , James M. Woods

IPC分类号： A61K31/4436 , A61K31/4245 , A61K31/4155 , A61K31/381 , C07D409/02 , A61P25/18 , A61P25/16 , A61P25/00 , A61P25/34 , A61P25/28 , C07D333/32 , A61K31/4025 , A61K31/422

CPC分类号： C07D333/38 , C07D409/12 , C07D413/12

摘要： Compounds of Formula (I) wherein E, A and R1 are as described in the specification, pharmaceutically-acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same.

摘要翻译： 式（I）的化合物，其中E，A和R 1如说明书中所述，药学上可接受的盐，制备方法，药物组合物及其使用方法。