公开(公告)号：US07022678B2

公开(公告)日：2006-04-04

申请号：US10058903

申请日：2002-01-28

申请人： Timothy Robert Hurley ,  Michael James Lovdahl ,  Brian Tobias

发明人： Timothy Robert Hurley ,  Michael James Lovdahl ,  Brian Tobias

IPC分类号： A61K31/7056 ,  C07H17/02

CPC分类号： A61K31/7056 ,  A61K47/555

摘要： In accordance with the present invention, there is provided pregabalin lactose conjugate compounds.Also provided as part of the present invention is a novel method of central nervous system disorders or diseases including seizure disorders, pain, depression, anxiety, sleep disorders, consumptive disorders, psychosis, tardive dyskinesia, Huntington's disease, or Parkinson's disease in a subject by administering to the subject a pharmaceutically effective amount of a pregabalin lactose conjugate.

公开(公告)号：US06800782B2

公开(公告)日：2004-10-05

申请号：US10256155

申请日：2002-09-25

申请人： Linna R Chen ,  Suresh R Babu ,  Claude Jeffrey Calvitt ,  Brian Tobias

发明人： Linna R Chen ,  Suresh R Babu ,  Claude Jeffrey Calvitt ,  Brian Tobias

IPC分类号： C07C1014

CPC分类号： C07C227/42 ,  C07C2601/14 ,  C07C229/28

摘要： Described are new crystalline anhydrous forms of gabapentin formed from gabapentin monohydrate. The new crystalline forms provide advantages in the manufacture of the therapeutic agent.

摘要翻译： 描述了由加巴喷丁一水合物形成的新的结晶无水形式的加巴喷丁。 新的结晶形式在治疗剂的制造中提供优点。