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    USE OF ANABOLIC AGENTS, ANTI-CATABOLIC AGENTS, ANTIOXIDANT AGENTS AND ANALGESICS FOR PROTECTION, TREATMENT AND REPAIR OF CONNECTIVE TISSUES IN HUMANS AND ANIMALS
    1.
    发明申请
    USE OF ANABOLIC AGENTS, ANTI-CATABOLIC AGENTS, ANTIOXIDANT AGENTS AND ANALGESICS FOR PROTECTION, TREATMENT AND REPAIR OF CONNECTIVE TISSUES IN HUMANS AND ANIMALS 有权
    抗生素，抗菌剂，抗氧化剂和用于人类和动物的连接组织的保护，治疗和修复的药物的使用

    公开(公告)号：US20100203177A1

    公开(公告)日：2010-08-12

    申请号：US12538000

    申请日：2009-08-07

    申请人： Todd R. HENDERSON ,  Carmelita FRONDOZA

    发明人： Todd R. HENDERSON ,  Carmelita FRONDOZA

    IPC分类号： A61K36/48 ,  A61K36/54 ,  A61P29/00 ,  C12N5/07 ,  C12N5/0786

    CPC分类号： A61K31/7008 ,  A61K31/56 ,  A61K31/737 ,  A61K36/48 ,  A61K36/54 ,  A61K2300/00

    摘要： The present invention relates to compositions for the modulation of inflammation in connective tissues in humans and animals and the modulation of markers of such inflammation, including COX-2, TNF-a, IL-1 (3, iNOS, p38, and chemokines, comprising any or all of anabolic, anti-catabolic, anti-oxidant and analgesic agents, including aminosugars, S-adenosylmethionine, arachadonic acid, GAGs, including pentosan, collagen type II, tetracyclines or tetracycline-like compounds, diacerin, super oxide dismutase, L-ergothioneine, methyl sulfanylmethane, one or more avocado/soybean unsaponifiables, and an analgesic, e.g., acetaminophen, and to methods of treating humans and animals by administration of these novel compositions to humans and animals in need thereof.

    摘要翻译： 本发明涉及用于调节人和动物结缔组织炎症的组合物，以及这种炎症的标志物的调节，包括COX-2，TNF-α，IL-1（3，iNOS，p38和趋化因子），其包含 合成代谢，抗分解代谢，抗氧化和止痛剂，包括氨基糖，S-腺苷甲硫氨酸，花生四烯酸，GAGs，包括戊聚糖，II型胶原，四环素或四环素样化合物，diacerin，超氧化物歧化酶，L - 甲基硫代甲烷，一种或多种鳄梨/大豆不皂化物，以及止痛剂，例如对乙酰氨基酚，以及通过将这些新型组合物施用于有需要的人和动物来治疗人和动物的方法。