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    Aminosugar, glycosaminoglycan, and S-adenosylmethionine composition for the treatment and repair of connective tissue
    6.
    发明授权
    Aminosugar, glycosaminoglycan, and S-adenosylmethionine composition for the treatment and repair of connective tissue 失效
    氨基糖，糖胺聚糖和S-腺苷甲硫氨酸组合物用于治疗和修复结缔组织

    公开(公告)号：US06271213B1

    公开(公告)日：2001-08-07

    申请号：US08797294

    申请日：1997-02-07

    申请人： Robert W. Henderson ,  Tarek Hammad

    发明人： Robert W. Henderson ,  Tarek Hammad

    IPC分类号： A61K31715

    CPC分类号： A61K45/06 ,  A61K31/7076 ,  A61K31/726 ,  A61K31/727 ,  A61K31/715 ,  A61K31/7004 ,  A61K2300/00

    摘要： A composition for the protection, treatment and repair and for reducing the inflammation of connective tissue in mammals and a method for the treatment of connective tissue in mammals by the administration of the composition. The composition includes S-Adenosylmethionine (SAM), and a component selected from an aminosugar or salts thereof (e.g., glucosamine) or glycosaminoglycans (e.g., chondroitin salts) or mixtures or fragments thereof. The composition optionally includes manganese which promotes the production of connective tissue matrix. The composition also optionally includes methyl donors or methyl donor cofactors, such as vitamin B12, vitamin B6, folic acid, dimethylglycine or trimethylglycine.

    摘要翻译： 用于保护，治疗和修复并减少哺乳动物结缔组织炎症的组合物和通过施用组合物治疗哺乳动物结缔组织的方法。 组合物包括S-腺苷甲硫氨酸（SAM）和选自氨基糖或其盐（例如葡糖胺）或糖胺聚糖（例如软骨素盐）或其混合物或片段的组分。 组合物任选地包括促进结缔组织基质生产的锰。 组合物还任选地包括甲基供体或甲基供体辅因子，例如维生素B12，维生素B6，叶酸，二甲基甘氨酸或三甲基甘氨酸。

    AMINOSUGAR, GLYCOSAMINOGLYCAN, AND S-ADENOSYLMETHIONINE COMPOSITION FOR THE TREATMENT AND REPAIR OF CONNECTIVE TISSUE
    7.
    发明申请
    AMINOSUGAR, GLYCOSAMINOGLYCAN, AND S-ADENOSYLMETHIONINE COMPOSITION FOR THE TREATMENT AND REPAIR OF CONNECTIVE TISSUE 审中-公开
    用于治疗和修复连接组织的氨基糖苷，谷氨酰胺糖和S-腺嘌呤金属组合物

    公开(公告)号：US20090291909A1

    公开(公告)日：2009-11-26

    申请号：US12473452

    申请日：2009-05-28

    申请人： Robert W. HENDERSON ,  Tarek Hammad

    发明人： Robert W. HENDERSON ,  Tarek Hammad

    IPC分类号： A61K31/7076 ,  A61P25/00

    CPC分类号： A61K45/06 ,  A61K31/7076 ,  A61K31/726 ,  A61K31/727 ,  A61K31/715 ,  A61K31/7004 ,  A61K2300/00

    摘要： A composition for the protection, treatment and repair and for reducing the inflammation of connective tissue in mammals and a method for the treatment of connective tissue in mammals by the administration of the composition. The composition includes S-Adenosylmethionine (SAM), and a component selected from an aminosugar or salts thereof (e.g., glucosamine) or glycosaminoglycans (e.g., chondroitin salts) or mixtures or fragments thereof. The composition optionally includes manganese which promotes the production of connective tissue matrix. The composition also optionally includes methyl donors or methyl donor cofactors, such as vitamin B12, vitamin B6, folic acid, dimethylglycine or trimethylglycine.

    摘要翻译： 用于保护，治疗和修复并减少哺乳动物结缔组织炎症的组合物和通过施用组合物治疗哺乳动物结缔组织的方法。 组合物包括S-腺苷甲硫氨酸（SAM）和选自氨基糖或其盐（例如葡糖胺）或糖胺聚糖（例如软骨素盐）或其混合物或片段的组分。 组合物任选地包括促进结缔组织基质生产的锰。 组合物还任选地包括甲基供体或甲基供体辅因子，例如维生素B12，维生素B6，叶酸，二甲基甘氨酸或三甲基甘氨酸。

    Aminosugar, glycosaminoglycan, and s-adenoslymethionine composition for the treatment and repair of connective tissue
    8.
    发明申请
    Aminosugar, glycosaminoglycan, and s-adenoslymethionine composition for the treatment and repair of connective tissue 审中-公开
    氨基糖，糖胺聚糖和s-腺苷甲硫氨酸组合物用于治疗和修复结缔组织

    公开(公告)号：US20080051366A1

    公开(公告)日：2008-02-28

    申请号：US11785915

    申请日：2007-04-20

    申请人： Robert Henderson ,  Tarek Hammad

    发明人： Robert Henderson ,  Tarek Hammad

    IPC分类号： A61K31/7076 ,  A61K31/726 ,  A61P29/00

    CPC分类号： A61K45/06 ,  A61K31/7076 ,  A61K31/726 ,  A61K31/727 ,  A61K31/715 ,  A61K31/7004 ,  A61K2300/00

    摘要： A composition for the protection, treatment and repair and for reducing the inflammation of connective tissue in mammals and a method for the treatment of connective tissue in mammals by the administration of the composition. The composition includes S-Adenosylmethionine (SAM), and a component selected from an aminosugar or salts thereof (e.g., glucosamine) or glycosaminoglycans (e.g., chondroitin salts) or mixtures or fragments thereof. The composition optionally includes manganese which promotes the production of connective tissue matrix. The composition also optionally includes methyl donors or methyl donor cofactors, such as vitamin B12, vitamin B6, folic acid, dimethylglycine or trimethylglycine.

    摘要翻译： 用于保护，治疗和修复并减少哺乳动物结缔组织炎症的组合物和通过施用组合物治疗哺乳动物结缔组织的方法。 组合物包括S-腺苷甲硫氨酸（SAM）和选自氨基糖或其盐（例如葡糖胺）或糖胺聚糖（例如软骨素盐）或其混合物或片段的组分。 组合物任选地包括促进结缔组织基质生产的锰。 组合物还任选地包括甲基供体或甲基供体辅因子，例如维生素B12，维生素B6，叶酸，二甲基甘氨酸或三甲基甘氨酸。

    Aminosugar, glycosaminoglycan or glycosaminoglycan-like compounds, and s-adenosylmethionine composition for the protection, treatment, repair, and reduction of inflammation of connective tissue
    9.
    发明授权
    Aminosugar, glycosaminoglycan or glycosaminoglycan-like compounds, and s-adenosylmethionine composition for the protection, treatment, repair, and reduction of inflammation of connective tissue 失效
    氨基糖，糖胺聚糖或糖胺聚糖样化合物，以及用于保护，治疗，修复和减少结缔组织炎症的s-腺苷甲硫氨酸组合物

    公开(公告)号：US06255295B1

    公开(公告)日：2001-07-03

    申请号：US08845852

    申请日：1997-04-28

    申请人： Robert W. Henderson ,  Todd Henderson ,  Tarek Hammad

    发明人： Robert W. Henderson ,  Todd Henderson ,  Tarek Hammad

    IPC分类号： A61K31715

    CPC分类号： A61K45/06 ,  A61K31/195 ,  A61K31/205 ,  A61K31/44 ,  A61K31/505 ,  A61K31/70 ,  A61K31/7004 ,  A61K31/714 ,  A61K31/715 ,  A61K33/32

    摘要： A composition for the protection, treatment and repair and for reducing the inflammation of connective tissue in mammals and a method for the protection, treatment of connective tissue in mammals by the administration of the composition. The composition includes at least two compounds selected from S-Adenosylmethionine (SAM), an aminosugar selected from the group consisting of glucosamine, glucosamine salts, glucosamine hydrochloride, galactosamine, N-acetylglucosamine, and fragments, mixtures or salts thereof, and a glycosaminoglycan or glycosaminoglycan-like compound selected from the group consisting of chondroitin, chondroitin salts, hyaluronic acid, glucuronic acid, iduronic acid, keratan sulfate, keratin sulfate, heparan sulfate, dermatin sulfate, PPS, sodium PPS, calcium PPS, oversulfated GAGs, and fragments, salts, and mixtures thereof. The composition optionally includes manganese which promotes the production of connective tissue matrix. The composition also optionally includes methyl donors or methyl donor cofactors, such as vitamin B12, vitamin B6, folic acid, dimethylglycine or trimethylglycine, and betaine.

    摘要翻译： 用于保护，治疗和修复并减少哺乳动物结缔组织炎症的组合物，以及通过施用组合物来保护，治疗哺乳动物中结缔组织的方法。 该组合物包括至少两种选自S-腺苷甲硫氨酸（SAM）的化合物，选自葡糖胺，葡糖胺盐，葡糖胺盐酸盐，半乳糖胺，N-乙酰葡糖胺及其片段，混合物或盐的氨基糖，以及糖胺聚糖或 选自软骨素，软骨素盐，透明质酸，葡糖醛酸，艾杜糖醛酸，硫酸角质素，硫酸角质素，硫酸乙酰肝素，硫酸皮肤素，PPS，PPS，PPS，PPS，过硫酸化GAG和片段的糖胺聚糖样化合物， 盐，及其混合物。 组合物任选地包括促进结缔组织基质生产的锰。 组合物还任选地包括甲基供体或甲基供体辅因子，例如维生素B12，维生素B6，叶酸，二甲基甘氨酸或三甲基甘氨酸和甜菜碱。