公开(公告)号：US20220364101A1

公开(公告)日：2022-11-17

申请号：US17623302

申请日：2020-07-03

Applicant: Tokushima University

Inventor： Kohji Itoh ,  Jun Tsukimoto

IPC: C12N15/52 ,  A61P3/00 ,  C12N15/86 ,  C12N9/48

Abstract: Provided are a modified-type neuraminidase, a gene encoding the modified-type neuraminidase, a combination of the modified-type neuraminidase and cathepsin A, a combination of the gene encoding the modified-type neuraminidase and a gene encoding cathepsin A, a vector including said genes, and a pharmaceutical composition containing same. The pharmaceutical composition can be used for the therapy of lysosomal storage disease.