公开(公告)号：US20210338809A1

公开(公告)日：2021-11-04

申请号：US17270561

申请日：2019-08-20

Applicant: Tokushima University

Inventor： Hiroshi Kido ,  Etsuhisa Takahashi ,  Takashi Kimoto ,  Satoko Sakai

IPC: A61K39/35 ,  A61K39/39 ,  A61P37/08

Abstract: An object of the present invention is to provide an allergen vaccine for treatment or prevention of an allergic disease, while reducing the risk of developing an immediate type allergy including anaphylaxis. The present inventors have found that (1) oral inoculation of a composition comprising a particular antigen (allergen) and SF10 into subjects having allergic diseases can suppress the development of an immediate type allergy caused by sensitization with the antigen, and (2) oral inoculation of a composition comprising a particular antigen (allergen) and SF10 into subjects not having allergic diseases can inhibit establishment of sensitization to the antigen, and have completed the present invention.