公开(公告)号：US11324809B2

公开(公告)日：2022-05-10

申请号：US16611883

申请日：2018-05-14

Applicant: Tokyo University of Science Foundation

Inventor： Yoichiro Iwakura ,  Tomonori Kaifu

IPC: A61K38/47 ,  A61P37/06 ,  A61P19/02

Abstract: Provided are: a pharmaceutical composition for curing, treating, or preventing a disease involving a biological mechanism controlled by a dendritic cell immunoreceptor, in which the pharmaceutical composition contains a carbohydrate modifying enzyme as an active ingredient; and a method of curing, treating, or preventing a disease involving a biological mechanism controlled by a dendritic cell immunoreceptor.

公开(公告)号：US10792300B2

公开(公告)日：2020-10-06

申请号：US15323748

申请日：2015-07-10

Applicant: TOKYO UNIVERSITY OF SCIENCE FOUNDATION

Inventor： Yoichiro Iwakura ,  Tomonori Kaifu ,  Rikio Yabe

IPC: A61K31/715 ,  C12N5/0784 ,  G01N33/50

Abstract: A dendritic cell immune receptor activator, comprising a compound having a sugar chain as an active ingredient, the sugar chain having a basic structure represented by the following formula: wherein, in the formula, a sialic acid does not exist at two non-reducing terminals, and each of x and y independently represents 3 or 4.

公开(公告)号：US20170143754A1

公开(公告)日：2017-05-25

申请号：US15323748

申请日：2015-07-10

Applicant: TOKYO UNIVERSITY OF SCIENCE FOUNDATION

Inventor： Yoichiro Iwakura ,  Tomonori Kaifu ,  Rikio Yabe

IPC: A61K31/715 ,  G01N33/50 ,  C12N5/0784

Abstract: A dendritic cell immune receptor activator, comprising a compound having a sugar chain as an active ingredient, the sugar chain having a basic structure represented by the following formula: wherein, in the formula, a sialic acid does not exist at two non-reducing terminals, and each of x and y independently represents 3 or 4.