专利检索 ap:("Tomokazu Nagano" OR "Ikue Kudo" OR "Takao Kawamura" OR "Mutsuo Taiji" OR "Hiroshi Noguchi" OR "Shunsuke Tani" OR "Hiroo Maeda") AND inv:"Ikue Kudo" 第 1 页

1.

发明授权
Method of treating ischemic disease by intramuscular administration of Hepatocyte growth factor 失效
标题翻译：通过肌内注射肝细胞生长因子治疗缺血性疾病的方法

公开(公告)号：US06887477B1

公开(公告)日：2005-05-03

申请号：US09762188

申请日：1999-08-04

申请人： Tomokazu Nagano , Ikue Kudo , Takao Kawamura , Mutsuo Taiji , Hiroshi Noguchi , Shunsuke Tani , Hiroo Maeda

发明人： Tomokazu Nagano , Ikue Kudo , Takao Kawamura , Mutsuo Taiji , Hiroshi Noguchi , Shunsuke Tani , Hiroo Maeda

IPC分类号： A61K38/18 , A61K38/00 , C07K14/00

CPC分类号： A61K38/1833

摘要： Preparations to be administered for treating or preventing ischemic diseases or arterial diseases which contain Hepatocyte growth factor (HGF) as an active ingredient. The preparations provide such effect that HGF concentration in an affected region to which HGF was administered is maintained, a half-life is longer, a dose can be reduced, and other organs except the affected region are less affected in comparison with intravenous administration.

摘要翻译： 用于治疗或预防含有肝细胞生长因子（HGF）作为活性成分的缺血性疾病或动脉疾病的制剂。所述制剂提供如下效果：维持HGF施用的受影响区域中的HGF浓度，半衰期更长，可以减少剂量，并且与静脉内施用相比，受影响区域以外的其它器官的影响较小。

2.

发明授权
Method for treatment of renal failure and occlusive lesion of blood vessels by administration of hepatocyte growth factor 失效
标题翻译：通过施用肝细胞生长因子治疗肾衰竭和血管闭塞性损伤的方法

公开(公告)号：US06869609B1

公开(公告)日：2005-03-22

申请号：US09555629

申请日：1998-12-03

申请人： Naoki Yamazaki , Tomokazu Nagano , Ikue Kudo , Michitoshi Sekine

发明人： Naoki Yamazaki , Tomokazu Nagano , Ikue Kudo , Michitoshi Sekine

IPC分类号： A61K38/18 , A61K38/00 , C07K14/00

CPC分类号： A61K38/1833

摘要： The invention presents a preparation for continuous intravenous administration containing hepatocyte growth factor (HGF) as an active ingredient. The preparation for continuous administration of the invention is effective at a lower dose as compared with single or frequent bolus administration of HGF, and therefore side effects can be reduced.

摘要翻译： 本发明提供了含有肝细胞生长因子（HGF）作为活性成分的连续静脉内给药的制剂。与单次或多次施用HGF相比，本发明的连续给药制剂在较低剂量下是有效的，因此可以降低副作用。

3.

发明授权
Method of treating rhabdomyolysis by administering hepatocyte growth factor 有权
标题翻译：通过肝细胞生长因子治疗横纹肌溶解症的方法

公开(公告)号：US06436388B2

公开(公告)日：2002-08-20

申请号：US09381031

申请日：2000-02-24

申请人： Ikue Kudo , Tomokazu Nagano

发明人： Ikue Kudo , Tomokazu Nagano

IPC分类号： A61K4500

CPC分类号： A61K38/1833

摘要： The present invention is drawn to a method of treating acute renal failure caused by rhabdomyolysis by administering a therapeutically effective amount of hepatocyte growth factor (HGF). The present invention is further drawn to a method of treating rhabdomyolysis by administering a therapeutically effective amount of hepatocyte growth factor (HGF).

摘要翻译： 本发明涉及通过施用治疗有效量的肝细胞生长因子（HGF）治疗由横纹肌溶解引起的急性肾功能衰竭的方法。本发明还涉及通过施用治疗有效量的肝细胞生长因子（HGF）来治疗横纹肌溶解症的方法。