公开(公告)号：US5874254A

公开(公告)日：1999-02-23

申请号：US822573

申请日：1997-03-19

申请人： Toru Imamura ,  Syuichi Oka ,  Kazuo Ozawa ,  Chieri Sato ,  Seigo Suzuki

发明人： Toru Imamura ,  Syuichi Oka ,  Kazuo Ozawa ,  Chieri Sato ,  Seigo Suzuki

IPC分类号： A61K38/00 ,  C07K14/50 ,  C12N15/16 ,  A61K38/18

CPC分类号： C07K14/50 ,  A61K38/00

摘要： The present invention relates to a novel FGF-5 analogous protein derived from mature mRNA formed by directly binding exon 1 to exon 3 in the splicing of a gene coding for FGF-5 protein as well as to a pharmaceutical composition containing the same as an active ingredient. The pharmaceutical composition containing the novel FGF-5 analogous protein of the present invention as an active ingredient can regulate physiological functions of FGF-5, such as regulation of restoration or development of hairs on the head and body, regulation of trophic and functional regulation in the brain and nervous system, proliferation of fibroblasts, etc.

摘要翻译： 本发明涉及从编码FGF-5蛋白的基因剪接中直接结合外显子1至外显子3而形成的成熟mRNA的新型FGF-5类似蛋白，以及含有该FGF-5蛋白的药物组合物 成分。 含有本发明的新型FGF-5类似蛋白质作为活性成分的药物组合物可以调节FGF-5的生理功能，例如调节头部和身体上毛发的恢复或发育，调节营养和功能调节 脑和神经系统，成纤维细胞的增殖等