公开(公告)号：US20140286868A1

公开(公告)日：2014-09-25

申请号：US14296676

申请日：2014-06-05

Applicant: Tuskegee University

Inventor： Clayton Yates ,  Timothy Turner

IPC: A61K49/00 ,  G01N33/50

CPC classification number: A61K49/0008 ,  C12Q1/025 ,  G01N33/5011 ,  G01N2500/04 ,  G01N2500/10

Abstract: Immortalized human cell lines derived from prostate cells are disclosed. Immortalized cells derived from a human epithelial prostate tissue cancer tumor are provided, as well as immortalized cells derived from healthy human epithelial prostate tissue from the same patient. Methods for utilizing such immortalized cell lines for researching, screening, and evaluating antimalignancy therapies and drug candidates are also disclosed.

Abstract translation: 公开了源自前列腺细胞的永生化人细胞系。 提供源自人上皮前列腺组织癌肿瘤的永生化细胞，以及衍生自来自同一患者的健康人上皮前列腺组织的永生化细胞。 还公开了利用这种永生化细胞系研究，筛选和评估抗偏倚药物和候选药物的方法。