公开(公告)号：US07057712B2

公开(公告)日：2006-06-06

申请号：US10602178

申请日：2003-06-24

申请人： Tyler J. Beck ,  Peter P. Hairston ,  Stanley L. Kaufman

发明人： Tyler J. Beck ,  Peter P. Hairston ,  Stanley L. Kaufman

IPC分类号： G01N21/64 ,  G01N21/53 ,  G01N15/02

CPC分类号： G01N21/645 ,  G01N15/1427 ,  G01N15/1459 ,  G01N21/47 ,  G01N21/64 ,  G01N2015/1438 ,  G01N2015/1486 ,  G01N2015/1493 ,  G01N2021/6419 ,  G01N2021/6421 ,  H01J49/40

摘要： Particle analyzing systems with fluorescence detection are disclosed, primarily in connection with particle sizing based on scattered light intensity or time-of-flight measurement. In one system, emission of fluorescence is used as a threshold for selecting particles for further analysis, e.g. mass spectrometry. In another embodiment, laser beams arranged sequentially along an aerosol path are selectively switched on and off, to increase the useful life of components, and diminish the potential for interference among several signals. Other embodiments advantageously employ color discrimination in aerodynamic particle sizing, single detectors positioned to sense both scattered and emitted fluorescent radiation, and laser beam amplitude or gain control to enhance the range of fluorescence detection.

摘要翻译： 公开了具有荧光检测的粒子分析系统，主要涉及基于散射光强度或飞行时间测量的粒子尺寸。 在一个系统中，荧光的发射被用作用于选择用于进一步分析的颗粒的阈值。 质谱。 在另一个实施例中，沿着气溶胶路径顺序地布置的激光束被选择性地打开和关闭，以增加部件的使用寿命，并且降低几个信号之间的干扰的可能性。 其他实施例有利地在空气动力学粒子尺寸选择中使用颜色鉴别，定位成感测散射和发射的荧光辐射的单个检测器以及激光束幅度或增益控制以增强荧光检测的范围。