公开(公告)号：US10928321B2

公开(公告)日：2021-02-23

申请号：US14383468

申请日：2013-03-08

申请人： UBIQUITOME LIMITED

发明人： Christopher Bruce Rawle

IPC分类号： G01N21/64 ,  B01L7/00 ,  B01L9/06 ,  C12Q1/686 ,  C12Q1/689 ,  C12Q1/70 ,  G02B27/14 ,  G01N21/15 ,  G01N21/03

摘要： An optical assembly 140 for a portable device for detecting molecule(s) within reaction vessels 110 comprises a collimator 403, a beam splitter arrangement and a plurality of guide arrangements 143. The collimator 403 collimates an excitation beam from an excitation source 400. The beam splitter arrangement splits the excitation beam from the collimator into a plurality of split excitation beams. Each beam splitter splits an incoming beam into two beams. In the case where the beam splitter arrangement comprises more than one beam splitter, the beam splitters are arranged in tiers such that a first tier comprises one beam splitter for receiving the excitation beam from the collimator, and each of the other tiers comprises one or more beam splitters. Each beam splitter in at least one of the other tiers receives a split excitation beam from a previous tier. Each guide arrangement 140 guides a respective one of the plurality of split excitation beams along an excitation path A from the beam splitter arrangement into a reaction vessel 110 containing a sample to stimulate an emission of a reaction light from the sample. Each guide arrangement 140 further guides reaction light from the sample along a detection path B towards a detector arrangement 142.

公开(公告)号：US20190262826A1

公开(公告)日：2019-08-29

申请号：US16406423

申请日：2019-05-08

申请人： Ubiquitome Limited

发明人： Christopher Bruce Rawle

IPC分类号： B01L3/00 ,  G01N21/64 ,  G01N21/03 ,  B01L7/00 ,  C12Q1/68

摘要： A reaction vessel holder (120) receives a reaction vessel (110). The reaction vessel (110) has a portion that is substantially optically transparent to light of a first range of wavelengths. The reaction vessel holder (120) comprises a body having a high thermal conductivity that is thermally coupled to and supports the reaction vessel (120). The body is further thermally coupled to a thermal device (130) for heating or cooling the reaction vessel holder (120) and thereby the reaction vessel (110). The body comprises a transparent portion that is substantially optically transparent to the light of the first range of wavelengths. The optically transparent portion of the reaction vessel (110) faces the transparent portion of the body such that light of the first range of wavelengths to and/or from the sample in the reaction vessel (120) can pass through the transparent portion.