公开(公告)号：US11059820B2

公开(公告)日：2021-07-13

申请号：US16615992

申请日：2018-05-24

Applicant: UCB BIOPHARMA SPRL

Inventor： Luc Lambert Jozef Jan Aerts ,  Georges Assaf ,  Nicolas Edmond Carly ,  Vincent Adolphe Carol Cool ,  Jean-Pierre Delatinne ,  Laurent Jacques Willy Delhaye ,  Jean Paul Kestemont ,  Sarah Le Meur

IPC: C07D471/04 ,  A61K31/519 ,  A61P3/00 ,  A61P9/00

Abstract: Crystalline forms of seletalisib, designated as Form B and Form F and characterized herein, being selective inhibitors of PI3 kinase enzymes, in particular of the human PBKδ isoform, are accordingly of benefit in medicine, for example in the treatment of inflammatory, autoimmune, cardiovascular, neurodegenerative, metabolic, oncological, nociceptive or ophthalmic conditions.